chapter 13
The two core symptoms of major depressive disorder.
What are depressed mood and loss of interest or pleasure?
The most psychoactive compound in cannabis.
What is Δ⁹-tetrahydrocannabinol (THC)?
The main neurotransmitter system affected by LSD.
What is serotonin (5-HT)?
SSRIs work through this mechanism.
What is blocking serotonin reuptake?
This cannabinoid is produced naturally in the body.
What is anandamide?
The neuropeptide associated with MDMA’s pro-social effects.
What is oxytocin?
This theory proposes that depression is caused by deficits in serotonin, norepinephrine, and dopamine.
What is the monoamine theory?
This theory suggests cannabis use may increase later use of other drugs.
What is the gateway theory?
This term describes the sensation of reliving hallucinogenic effects long after the drug is gone.
What are flashbacks?
This class of antidepressants carries a dietary risk of hypertensive crisis.
What are MAOIs (Monoamine oxidase inhibitors)?
Two acute effects of cannabis use.
What are impaired short-term memory and increased appetite?
The main mechanism of action for ketamine.
What is NMDA receptor blockade?
This brain region regulates negative emotions and is overactive in depression.
What is the lateral habenula?
Chronic high-dose cannabis use can cause this syndrome.
What is amotivational syndrome?
The hallucinogen known for acting on kappa opioid receptors rather than serotonin receptors.
What is salvinorin A (from Salvia divinorum)?