Endo
This rare cause of hyperthyroidism features autonomous nodules with heterogeneous uptake on thyroid scan.
What is toxic multinodular goitre (Plummer disease)?
A patient with high fever, retro-orbital pain, severe myalgia, and a positive tourniquet test most likely has this viral infection.
What is dengue fever?
First-line pharmacotherapy for PTSD
what are SSRIs?
This autosomal dominant condition causes bilateral renal cysts and may present with subarachnoid hemorrhage.
What is autosomal dominant polycystic kidney disease (PKD1/PKD2)?
This HLA allele is associated with ankylosing spondylitis
what is HLA-B27?
This diabetic medication carries the highest risk of euglycaemic ketoacidosis.
What is an SGLT2 inhibitor?
A man goes swimming in SE Asia, then presents with jaundice, renal failure, and conjunctival suffusion.
What is leptospirosis (Weil’s disease)?
This personality disorder is characterized by grandiosity and lack of empathy
what is narcissistic personality disorder?
MAHA, thrombocytopenia, renal failure and ADAMSTS13 <10 in an adult without diarrheal prodrome suggests this diagnosis.
What is thrombotic thrombocytopenic purpura (TTP)?
A 70-year-old with headache, jaw claudication, and elevated ESR is at risk of irreversible blindness if this condition isn’t treated promptly.
What is giant cell arteritis?
This hormone is secreted in response to hypoglycaemia and acts to oppose insulin via hepatic glucose output.
What is glucagon?
The most common cause of culture-negative endocarditis following farm animal exposure.
What is Coxiella burnetii (Q fever)?
This personality disorder is marked by unstable relationships, impulsivity, and recurrent suicidal behavior.
What is borderline personality disorder?
This renal tubular disorder causes hyperkalaemic normal-anion-gap metabolic acidosis in diabetic patients with low aldosterone levels
What is Type 4 (hyperkalaemic) renal tubular acidosis?
Positively birefringent, rhomboid-shaped crystals under polarized light microscopy.
What is pseudogout (CPPD disease)?
The triad of medullary thyroid carcinoma, pheochromocytoma, and mucosal neuromas
what is MEN2B?
The Jarisch–Herxheimer reaction classically occurs after treatment of this spirochaetal infection.
What is syphilis (Treponema pallidum)?
will also accept leptospirosis as an alternate answer
This antipsychotic carries the highest risk of agranulocytosis.
What is clozapine?
A young man presents with hematuria and deafness. Renal biopsy reveals basket-weave thickening of the GBM.
What is Alport syndrome?
This cytokine is the main target of tocilizumab
what is IL-6?
This condition features elevated 17-hydroxyprogesterone, salt-wasting, and virilisation in females.
What is 21-hydroxylase deficiency (classic CAH)?
The most reliable early laboratory clue distinguishing severe dengue from other viral illnesses is a falling platelet count with this concurrent change.
What is rising haematocrit (haemoconcentration)?
The risk of serotonin syndrome rises when SSRIs are combined with this migraine drug
what is triptans?
This inherited cause of metabolic alkalosis and hypokalemia mimics thiazide use.
What is Gitelman syndrome?
The most specific antibody for RA, often preceding disease onset.
What is anti-CCP (anti-cyclic citrullinated peptide)?