Facts
Abbreviation for gene editing technology that we are talking about today
CRISPR
The Cas9 protein acts as a molecular "scissors" to do this to the DNA
Cut DNA
The molecule that carries genetic information in all living organisms
DNA
100
Answer here
CRISPR has been used to create genetically modified versions of this insect, which transmits disease, specifically, malaria
mosquito
One limitation of CRISPR:
CRISPR editing can fail
Ethics: by creating more resistant crops, editing genes in humans, there are questions regarding human safety and side effects
Unknown environmental and long-term consequences
This biologist is known for developing the theory of evolution by natural selection
Charles Darwin
Which protein is most commonly associated with CRISPR and is used for gene editing
Cas9
In CRISPR, this molecule guides the Cas9 protein to the correct location in the DNA to make a cut
guide RNA
This is the powerhouse of the cell, responsible for producing energy
mitochondrion
CRISPR stands for...
CRISPR: Clustered Regularly Interspaced Short Palindromic Repeats
The "guide RNA" directs the Cas9 protein to a specific location on the DNA based on this structure
DNA sequence
CRISPR is being researched as a possible treatment for this viral disease, which attacks the immune system
HIV
Who were awarded the Nobel Prize for their groundbreaking work on CRISPR in 2020
Emmanuelle Charpentier and Jennifer A. Doudna
CRISPR Process:
1)Guide RNA is created the lab- This RNA is used to guide the Cas9 to the area that is being cut
2)DNA is cut- Guide RNA binds to the target DNA and the Cas9 cuts the DNA like scissors
3)Repair- The DNA is repaired with the new edits
- Mutation, Deletion, Insertion
This system is responsible for defending the body against pathogens
immune system