Axial Skeleton
Muscular System
Limb Development
Birth Defects
Cardiovascular
100

Which (specific) germ layer gives rise to the axial skeleton?

The paraxial mesoderm (plus some lateral mesoderm and neural crest cells)

100

The part of the somite that forms muscle tissue

Myotome

100

Maintains a pool of rapidly dividing cells in the undifferentiated zone

Apical epidermal ridge (AER)
100

Group of anomalies that occur together due to a specific cause

syndrome

100

Muscular middle layer of the heart tube

myocardium

200

The membranous neurocranium ossifies by which method?

Intramembranous

200

Transcription factor responsible for differentiation of muscle cells in the ventromedial region of the somite

MyoD

200

Area that directs anteroposterior patterning in the limbs

zone of polarizing activity (ZPA)

200

Viral infection that can lead to severe microcephaly

Zika

200

Region that will become the left ventricle and part of the atria

the primary heart field

300

Axial skeleton defect where the cranial sutures prematurely fuse.

Craniosynostosis

300

Transcription factor responsible for smooth muscle differentiation

serum response factor

300

Forms humerus in the forelimbs and femur in the hindlimbs

stylopod

300

Leading cause of intellectual disability in infants

alcohol exposure

300

The region that will become the right ventricle, part of the atria, and the outflow tract

the secondary heart field

400

The developmental process of the caudal half of a sclerotome fusing with the cephalic half of the one underneath it

Resegmentation

400

These structures are derived from sclerotome and differentiate due to expression of scleraxis

tendons

400

Fusion of digits due to failure of intervening tissue to be eliminated via apoptosis

Syndactyly

400

Protein detected in maternal serum used to detect chromosomal abnormalities, neural tube defects, and abdominal wall defects

alpha-fetoprotein

400

Precursor cells that travel to the epiblast to form the cardiogenic region in the ventral layer of the lateral mesoderm

Progenitor heart cells

500

This structure in the vertebral column is the only part of the notochord which remains in the adult

Nucleus pulposus

500

VML cells that cross this barrier mix with lateral plate mesoderm to form the abaxial musculature

The lateral somitic frontier
500

Transcription factor that directs synovial joint formation

Wnt14

500

Isolation of fetal cells or DNA from maternal circulation

Noninvasive Prenatal Screening

500

Suspends the heart tube during early development

Dorsal mesocardium

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