Growth Hormone
What to give?
Deficit
Deficit = Somatropin
What meds to give for excess?
Meds: Lancriatide and Bromocriptine
Used to treat?
Hypothyroidism (hashimoto's and myxedema)
- Hypo= low and slow
Levothyroxine BBW?
Thyroid replacement is not used to treat obesity
HyperTSH treatment?
Surgical removal of thyroid, radioactive therapy, beta blocker, anti-thyroid meds?
Hyper = high and hot
How to give Somatropan for Deficit?
SQ; Never PO; Daily injections
Treatment for Excess GH?
Excess = Surgery, Radiation, or give meds to decrease growth hormone
Low TSH: ___ and ____
T3 and T4
Levothyroxine Teaching?
Do not stop abruptly
HyperTSH 3 meds?
1) Methimazole
2) Proplythiouracil
3) Potassium Iodine (Lugol)
GH Deficit (Somatropin) Side Effects?
hyperglycemia, pancreatis, joint pain, and muscle pain
What does Bromocriptine also treat?
Male gynacomastea
Meds for hypo-TSH?
Levothyroxine
Levothyroxine Monitor?
Monitor TSH and T4 levels
HyperTSH: Methimazole
Perffered drug
- 10x more potent
- SE: drowsiness, jaundice, vertigo, HA, GI and heptatoxcicity
GH Deficit (Somatropin) when to stop treatment?
When the growth plates close, ephysis closes
How is Depo Lamcriatide given?
IM every 4 weeks
Levothyroxine Mnemonic
LEVO
L: life long drug, long onset(3-4 weeks)
E: early morning empty stomach
V: very hyper, report symptoms of hyperthyroidism
O: oh the baby is fine - safe for pregnancy
How long do thyroid meds take to work?
up to 6 weeks
HyperTSH: Proplythiouracil
Required dosing several times per day
- SE: blood dyscreasis, rash, GI distress, and hepatotoxcicity
GH Deficit (Somatropin) what to monitor?
Monitor growth rate and bone age
Depo Side Effects?
HA, N/V/D, flatus, and bloating
Levothyroxine Side Effects?
None- unless given too much and you will see hyperthyroidism (hair loss, bulging eyes, GI distress, sweating, weight loss, heat intolerance)
Levothyroxine: is it a cure?
NO
HyperTSH: Potassium Iodine (Lugol)
Absorbed by thyroid gland to inhibit production and release of hormones
- SE: bad metallic taste, severe GI distress, stomatitis, stains teeth (drink with straw)