Anatomy/Embryo/Histo
Pituitary
Adrenal
Thyroid
First Aid / Grab Bag
100
The adrenal medulla is derived from these embryological cells
Neural crest cells
100
This hypothalamic hormone inhibits the secretion of prolactin
Dopamine (aka PIF - prolactin inhibiting factor)
100
This part of the adrenal cortex is not responsive to ACTH
What is the zona glomerulosa
100
These cells secrete calcitonin
What are the parafollicular cells (C-cells)
100
This symptom is pathognomonic for Grave's disease
What is opthalmopathy (proptosis, EOM swelling)
200
These are the secretory products of the basophil cells of the anterior pituitary.
"B-FLAT" Gonadotrophs - FSH/LH Corticotrophs - ACTH Thyrotrophs - TSH
200
The hypothalamic hormone somatostatin has inhibitory effects on these 2 hormones from the anterior pituitary gland.
What are GH and TSH
200
The most common tumor of the adrenal medulla in children
What is neuroblastoma
200
Pregnancy has this effect on TBG
What is an increase.
200
PTU inhibits this enzyme which methimazole does NOT inhibit.
What is 5'-deiodinase
300
These named structures found in the posterior pituitary are dilated terminals of axons that store ADH and oxytocin
What are Herring bodies
300
Regulation of ADH secretion from the posterior pituitary is most sensitive to change in this
serum osmolality
300
MEN Types 2A and 2B are associated with this tumor of the adrenal gland.
What is pheochromocytoma
300
The iodide pump is located on this surface of the follicular cell.
What is the basolateral surface.
300
Ketoconazole inhibits this enzyme of steroidogenesis
What is desmolase
400
Beware of damaging these 2 structures when doing a thyroidectomy (Hint: not blood vessels)
What are the recurrent laryngeal nerve and the parathyroids
400
This pituitary tumor may be effectively treated by the use of medication alone
What is a prolactinoma (Dopamine agonists)
400
A 60 year old 60 pack-year smoker comes in with classic symptoms of Cushing's syndrome. A dexamethasone test is performed and both low and high doses fail to suppress elevated ACTH levels. This is the most likely etiology of his condition.
What is ectopic ACTH production from a small cell lung cancer.
400
A 35 year old female presents with a diffuse goiter and hyperthyroidism. You suspect these relative values of TSH and thyroid hormones respectively
What are low and high
400
A patient with a hyperfunctional adrenocortical adenoma is undergoing surgery and has a hypotensive crisis during the operation. Dosing with this hormone would have prevented the hypotensive crisis.
What is hydrocortisone
500
The superior and inferior divisions of the parathyroid arise from these pharyngeal pouches respectively
What are the 4th and 3rd
500
These 6 pituitary hormones stimulate their targets via activation of cAMP signaling pathways
What are FSH, LH, ACTH, TSH, MSH, ADH (V2 receptor)
500
You see 2 patients: one with primary adrenal insufficiency, and the other with secondary adrenal insufficiency. Without conducting any tests and only by visual inspection, you should be able to tell which patient has which condition by noticing this feature in the patient with primary adrenal insufficiency.
What is hyperpigmented skin.
500
If a patient has been experiencing hyperthyroid symptoms for a period longer than this duration, you can safely rule out thyroiditis as a cause.
What is 6 months.
500
You see a 55 yo man who reports having to buy larger sized shoes recently. You notice prominence of the brow line and a widened nasal bridge. Your suspected diagnosis may be confirmed with this suppression test.
What is an oral glucose tolerance test.
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