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"Imagine that you are Fay Wray in King Kong's enormous hand, screaming and struggling in terror, in the 1933 science fiction classic. If someone could measure your heart rate, blood pressure, and blood levels of corticosterone and glucose, the readings would be off the charts. These same physiological responses to acute fear and stress occur in animals such as rats, mice, rabbits, monkeys, and other species commonly used in laboratory experiments. The experience of being picked up by a human experimenter may be every bit as fearsome as being palmed by King Kong."
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