Terminology/Vocabulary

Use Case/Applications

ELSI of epigenetics research

100

Evidence-based tools that supplement clinical counseling and help patients make health choices that include their personal values.

What are patient decision aids (PDA)?

100

The spearhead for the potential applications of epigenetics in clinical management.

What is cancer epigenetics?

100

The key to improving healthcare.

What is communication between clinician and patient?

200

The IHEC focuses on setting up a global human epigenome reference. IHEC stands for…

What is the International Human Epigenome Consortium?

200

Potential integration of the ethical schools of thought (biomedical ethics and environmental ethics).

What is epigenetics?

200

The main ethical issues associated with use of epigenetic-based biomarkers in disease assessment.

What are patient autonomy, privacy and confidentiality, personal responsibility for health, and justice and equality of opportunities for health promotion?

300

Personal behavior and habits have an influence on offspring generations ahead, through the epigenetic profiles of the gametes.

What is transgenerational epigenetic inheritance?

300

Type of informed consent that includes limited consent, complexity, and multiple information sessions.

What is the tiered-layered-staged consent model?

300

Four points proposed by the IHEC Bioethics Working Group to be met before communicating epigenetic information.

What are data accuracy, stability of epigenetic-based biomarker, causality of the epigenetic mark, and clinical value of the biomarker?

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