Units of Measurement
Reduce 1.256 g to micrograms, to milligrams, and to kilograms.
Micrograms (mcg) 1,256,000
Milligrams (mg) 1,256
Kilograms (kg) 0.001256
*question 4 Dr. P*
If 500mL of ferric chloride solution weighs 650g, what is its specific gravity
1.300
*Question 5 Dr. Yang*
If 100mL of a pharmaceutical preparation contains 20microliters of a 50% w/v solution of benzalkonium chloride, what is the percentage strength of that agent in the solution?
0.01%
*Question 4 Dr. Yang*
Agenerase oral solution contains 1.5% amprenavir. A pharmacist wished to change the drug concentration to 5mg/mL by using a diluent of polyethylene glycols. How many milliliters of the oral solution and how many milliliters of the diluent should be used to prepare 8 fluid ounces of the mixture
78.9 mL Agenerase
157.71 mL polyethylene glycols
What is the concentration, in milligrams per milliliter, of a solution containing 2 mEq of potassium
chloride (KCl) per milliliter?
149mg/mL
*Slide 16 Dr. P*
A liquid contains 0.25 mg of a substance per milliliter. How many grams of the substance will 3.5 L contain?
0.875 grams (g)
*question 8 Dr. P*
What is the volume, in mL, of 1 kg of sulfuric acid with a specific gravity of 1.83
546.45 mL
*Question 23 Dr. Yang*
A blood volume expansion solution contains 6% (w/v) of hetastarch and 0.9% (w/v) of sodium chloride. How many grams of each agent would be present in 250 mL of the solution?
15g-Hetastarch
2.25g-NaCl
*Question 19 Dr. Yang*
The formula for a buffer solution contains 1.24% w/v of boric acid. How many milliliters of a 5% w/v boric acid solution should be used to obtain the boric acid needed in preparing 1 liter of the buffer solution?
248mL
*Question 17 Dr. Yang*
What is the concentration, in grams per milliliter, of a solution containing 4 meq of calcium chloride (CaCl2*2H2O) per milliliter?
Z=147
0.294 g/mL
*Slide 18 Dr. P*
How many grams of digoxin (Lanoxin) would be required to make 25,000 tablets each containing 250 mcg of digoxin?
6.25 grams (g)
*question 17 Dr. P*
Two 10-mL samples of urine have specific gravities of 1.003 and 1.030. What is the difference in weight, in mg, between the two samples?
Sample B is 270 mg more than sample A
*Question 28 Dr. Yang*
If 100mL of a solution for a patient-controlled anesthesia contains 200 mg of morphine sulfate and 8mg of droperidol, calculate the percentage strength of these ingredients in the solution
Droperidol: 0.008%
Morphine: 0.2%
*Question 26 Dr. Yang*
How many milliliters of a 0.2% solution of a skin-test antigen must be used to prepare 4mL of a solution containing 0.04mg/mL of the antigen
0.08mL
*Question 47 Dr. Yang*
A solution contains 5% of anhydrous dextrose (Z = 180 g) in SWFI. How many mosm/L are represented by this concentration?
277.778 mOsm
*Slide 26 Dr. P*
A 10-mL graduate weighs 42.745 g. When 5 mL of distilled water are measured in it, the combined weight of graduate and water is 47.675 g. By definition, 5 mL of water should weigh 5 g. Calculate the weight of the measured water and express any deviation from 5 g as a percentage of error.
1.4%
*Question 63 Dr. P*
Cocoa butter (Theobroma oil), which is solid at room temperature and melts at 34 degrees Celsius, has a specific gravity of 0.86. If a formula calls for 48mL of Theobroma oil, what would be the corresponding weight of cocoa butter to use?
41.28 g
*Question 31 Dr. Yang*
If a city water supply has a limit of 250 ppm of nitrate ion, what is the maximum amount of nitrate ion, in grams, that may be present in a 10,000-gallon reservoir?
9462.5g
*Question 69 Dr. Yang*
How many milliliters of a 2.5% w/v chlorpromazine HCl injection and how many milliliters of 0.9% w/v sodium chloride injection should be used to prepare 500mL of a 0.3% w/v chlorpromazine HCl injection?
60 mL of Chlorpromazine HCl
440 mL sodium chloride injection
*Question 61 Dr. Yang*
How many milliosmoles of sodium and how many milliosmoles of chloride are represented in 2 L of 3% hypertonic NaCl (MW = 58.5) solution? Assume complete dissociation. (Round to two decimal places)
1,025.64 mOsmol Na+
1,025.64 mOsmol Cl-
A formula calls for 0.6 mL of a coloring solution. Using a 10-mL graduate calibrated from 2 to 10 mL in 1-mL units, how could you obtain the desired quantity of the coloring solution by the aliquot method? Use water as the diluent
LMQ = 2 milliliters (mL)
Multiplier = 10
Drug measure = 2 milliliters (mL)
Diluent volume = 8 milliliters (mL)
Total mixture volume = 10 milliliters (mL)
Final measure volume = 3 milliliters (mL)
Measure 2 milliliters (mL) of the coloring solution. Measure 8 milliliters (mL) of the water. Mix the coloring agent and water thoroughly for a total 10 milliliters (mL) of mixture. Measure 3 milliliters (mL) of the final mixture, which will contain 0.6 milliliters (mL) of the coloring solution.
*Question 57 Dr. P*
The formula for 1000g of polyethylene glycol ointment calls for 600g polyethylene glycol 400. At $19.15 per pint, what is the cost of the polyethylene glycol 400, specific gravity 1.140 needed to prepare 4000g of the ointment?
Total volume= 2105mL
Cost= $85.23
*Question 33 Dr. Yang*
If a commercially available insulin preparation contains 1ppm of proinsulin, how many micrograms of proinsulin would be contained in a 10-mL vial of insulin
10 micrograms
*Question 70 Dr. Yang*
Zephiran Chloride solution (17%w/v) q.s
Purified water to make 480 mL
Sig: One tbsp. diluted to 1 gallon with water to make a 1:10,000 dilution
How many milliliters of Zephiran chloride solution should be used in preparing the prescription?
71.2mL
*Question 67 Dr. Yang*
A patient has a sodium deficit of 172 meq. How many milliliters of isotonic NaCl (MW = 58.5) solution should be administered to replace the deficit? (Round to the nearest whole number)
1,118 mL