Across The Lifespan
Gross malformations, neurobehavioral and metabolic anomalies
What is Teratogenesis
the name is not owned by any drug company and is universally accepted.
What is nonproprietary?
Absorption, Distribution, Metabolism and Excretion
What is the pharmacokinetic phase?
The relationship between too much drug and not enough
What is the therapeutic index?
The collection of subjective and objective data
What is Assessment?
Metabolize drugs faster than adults
What is the rate of metabolism for a 1 yo and older
Requires drug manufacturers to test certain drugs and biologic products for their safety and effectiveness in children.
What is the Pediatric Research Equity Act?
The breakdown of oral drug form into small particles.
What is disintegration?
mimics or impersonates a naturally occurring neurotransmitter
What is an agonist?
setting SMART goals, establishing priorities and criteria for therapeutic success
What is the planning step of the nursing process?
Due to immature state of 5 pharmacokinetic processes.
What is the increased sensitivity of drugs in infants due to?
effective, safe and selective
What are properties of an ideal drug
drug passes through the GI tract to the liver and metabolized to an inactive form then excreted
What is the First Pass Effect?
Blocks receptors to prevent receptor activation
What is an antagonist?
Risk for bleeding related to accidental arm amputation
What is a nursing diagnosis?
decreased hepatic metabolism, increase in half-life of some drugs, increased response to oral drugs, decrease in first pass effects
What is altered in geriatric metabolism of drugs?
Responsible for ensuring...
1. accurate labeling
2. effectiveness
3. tested for harmful effects
What is The Federal Drug Administration
less than 10% of a drug is free to exert a therapeutic effect.
What is a highly protein bound drug?
Drugs that affect multiple receptors in similar body tissues.
What is a nonselective drug?
Chronic Obstructive Pulmonary Disease
What is a medical diagnosis?
inadequate supervision, increased individual variations, low therapeutic index medications, drug accumulation, polypharmacy and chronic illness
What are attributing factors to adverse drug reactions in the geriatric client?
5 Rights Plus 5 and 3 checks
What is the right patient, medication (x3), dose, route, time, assessment, documentation, evaluation, education and right to refuse?
used to determine the dosing interval or to ensure a Steady State
What a drug half life?
Drugs that affect many receptor sites
What is nonspecific?
Drug administration, Patient care and education
What are examples of the implementation step in the nursing process