HW02
Observations in the group are unrelated and not matched in any meaningful way. (Example women's and men's shoes differences)
Independent data
Number of individuals or observations included in a research study
sample size
This effector cell produces cytokines IFN gamma and targets macrophage cells and host defense is ________
Th1
Intracellular pathogens
Inhibitory receptor for down stream blocking of activated T cells
PD-1
Antigen recognition express ______ proteins (anti-apoptotic)
BcL-2
Observations in the groups are matched in a meaningful way (same pigs with the SS catheter standard and the new catheter)
Paired data or dependent data
The differences between the population parameter and the null hypothesis
The effect of the study
This effector cell produces cytokines IL-4, IL-5, and IL-13 and targets eosinophils cells and host defense is ________
Th2
Helminths
Non-APC mutates into cancer cells, it relies on this for DCs to present cancerous antigens
Cross presentation
This portion gives selectivity to the secreted antibodies __________
This portion gives effector functions to the secreted antibodies __________
Fab portion
Fc portion
_______ is when we reject the null hypothesis that IS actually true, resulting in an incorrect conclusion, that IS a significant difference between the groups when there IS not.
Type 1 error (False positive)
__________ is when we accept a false null hypothesis resulting in an incorrect conclusion, there is NOT significant difference between the experimental and control groups when there IS.
Type 2 error (false negative)
This effector cell produces cytokines IL-17 and IL-22 and targets neutrophils cells and host defense is ________
Th17
Extracellular bacteria and fungi
The mitochondrial apoptotic pathway is regulated by the oncogenic family of genes
BcL family (BcL-2)
These antibodies activate the complement proteins
IGg1
IGg2
IGg3
IgM
________ is a statistical method to determine if a value is significantly higher or lower than a mean value. It's associated with the __________.
one-tailed test
Alternative hypothesis
Determine the minimum sample size required for a research study
Power analysis
This effector cell produces cytokines IL-22 (INF gamma and IL-4) and targets B cells and host defense ________
Tfh (T follicular helper cell)
Extracellular pathogens
Molecules that become immunogenic when bound to a carrier
Haptens
These antibodies have low affinity
FCgammaRII A/C
FCgammaRIII A/B
FCgammaRIIB
________ is a statistical method to determine if there is a significant difference between two groups without specifying the direction of the difference. It's associated with the____________.
two-tailed tested
null hypothesis
Cells that strongly bind to self antigens_____
Cells that weakly bind to self antigens_______
Positive selection
Cytokines stimulate development and expansion on their respective subset
Polarization
Promotes proliferation of CD8+ cells_______
Differentiation of effector CD8+ cells______
Survival of CD8+ cells________
Differentiation of CD8+ cells_______
IL-2
IL-12
IL-15
IL-21
Reduce inhibition by setting up block
Checkpoints inhibitors