Pharmacology
Liver Dysfunction Medications
Hepatitis
Cirrhosis
Delegation
100
Overdose of this drug is one of the major causes of liver dysfunction

Unintentional Tylenol Overdose

100

Lactulose use, action, and routes

Cirrhosis, Hepatic Encephalopathy

Acidifies intestine to ionize ammonia and excrete it through stool

PO, PR, NG (liquid medication)

100

General treatment for Hepatitis

Rest, supportive treatment (it's a virus)

100

Cirrhosis Diet

High calorie, mod-low fat, increased carbs, protein supp, low Na (with ascites/edema), B Vitamins

100

(T/F) UAPs can assist with placement of braces and prostheses

True

200

Steroids must be tapered to avoid this 

Adrenal crisis (severe hypotension/shock, hypoglycemia, hyponatremia, hyperkalemia, weakness, confusion, lethargy, coma, n/v, abdominal pain)

200

Class, action and use of Rifaximin

Class: Antibiotic

Action: reduce ammonia production by eliminating ammonia-producing colonic bacteria

Use: Tx or prevention of HE in ESRD

200

Precautions for Hep A, Hep B and Hep C

Hep A: contact

Hep B and C: Standard

200

Most common causes of cirrhosis

Alcohol, chronic Hep C, NASH

200

(T/F) LPNs can receive a verbal order from the provider

False

300
The four phases of pharmacokinetics

Absorption (how it reaches bloodstream), Distribution (movement of medication to tissues), Metabolism (liver), Excretion (kidneys)

300

Class and use of spironolactone

Class: potassium-sparing diuretic (aldosterone antagonist)

Use: Cirrhosis of liver with ascites; fluid retention

300

This complication is most likely to occur from Hep C

Cirrhosis

Also: liver failure/cancer, portal HTN, varices, peripheral edema and ascites

300

This is the most life-threatening complication of Cirrhosis (and why)

Esophageal Varices d/t inadequate clotting factors and Vitamin K

300

(T/F) It is appropriate for the RN to teach the patient about a new medical diagnosis

True- The provider gives the actual diagnosis. 

Extra: LPN can reinforce RN's initial teaching after

400

Steroid administration routes ("extra points" for examples of each route)

Inhaled (fluticasone), eye drops, PO (prednisone), IM (emergency kits for Addison's patients), IV (methylprednisolone), Topical (hydrocortisone cream)

400

** Bonus Question **

What is oncotic pressure?

Force exerted by proteins in blood plasma that draws fluid back into capillaries from the surrounding tissues

400

Timeframes for giving Immunoglobulin for Hep A vs Hep B

Hep A: within 2 weeks of exposure

Hep B: within 24 hours

400

Increase or decrease in these VS with cirrhosis: BP, HR, RR, T, 02, Pain

Decreased BP, Increased Pulse, increased RR, Temp WNL, decreased 02, general discomfort
400

(T/F) The UAP can place the patient's nasal cannula in their nares

True- the UAP can not turn on/off the actual oxygen

500

Steroid Diet

Low Na, high protein (wound healing, suppress appetite), high Ca (risk of osteoporosis), high K (steroids cause hypokalemia), decreased simple carbs (risk of hyperglycemia)

500

Purpose of administering IV Serum Albumin

ESLD - to help pull fluid out of pleural spaces

500

Who else should get the immunoglobulin for Hep A vs Hep B

Hep A: household, daycare

Hep B: newborns if mom is positive, needle sticks, sexual exposure (check titers to determine immunity)

500

The four main symptoms a patient would come to the hospital when they have Cirrhosis (and what caused them)

Mental status changes (HE)

SOB (ascites)

GI Bleed (varices) 

AKI (hepatorenal syndrome)

500

The five rights of Delegation

Right task, right circumstance, right person, right direction/communication, right supervision/evaluation

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