Platelet formation and function in clotting
Where does hematopoiesis occur in adults?
A. Liver
B. Bone marrow
C. Spleen
D. Endothelial cells
B. Bone marrow
structure and function of the hematologic system slide 11
Which of the following is a common second messenger in hormone signaling?
A. DNA
B. Cyclic AMP (cAMP)
C. Hemoglobin
D. Albumin
B. Cyclic AMP (cAMP)
hormones #2 slide 9
Hormone secretion (availability) is not tightly regulated by which of the following?
A. Hormone degradation and excretion
B. Neuroendocrine reflexes
C. Negative feedback control
D. Circadian rhythm
A. Hormone degradation and excretion
endocrine physiology slide 10
What symptom of hypothyroidism is to blame for the associated edema of the extremities?
A. Muscle weakness
B. Bradycardia
C. Constipation
D. Hyperreflexia
A. Muscle weakness
What stimulates renin release from the kidneys?
A. High blood volume
B. Low blood pressure
C. Increased blood glucose
D. High oxygen levels in blood
B. Low blood pressure
hormones #2 slide 13
Which hormone maintains platelet levels?
A. Erythropoietin
B. Thrombopoietin
C. Insulin
D. Calcitonin
B. Thrombopoietin
slide 18
What is not a purpose of a second messenger in hormone signaling?
A. To transport hormones in the blood
B. To intensify strength of hormone signal
C. To carry out hormone effects
A. To transport hormones in the blood
hormones #2 slide 9
Which hormone released from the hypothalamus eventually stimulates the sertoli cells?
A. Corticotropin releasing hormone (CRH)
B. Thyroid releasing hormone (TRH)
C. Gonadotropin-releasing hormone (GnRH)
D. Growth hormone releasing hormone (GHRH)
C. Gonadotropin-releasing hormone (GnRH)
hormones #2 slide 7
What happens to metabolism in a person with low thyroid hormone levels?
A. Metabolism increases significantly
B. Metabolism slows down
C. Blood pressure immediately drops to zero
D. Platelet production increases
B. Metabolism slows down
alterations in the endocrine system slide 8
Renin converts which substance into angiotensin I?
A. Angiotensin II
B. Aldosterone
C. Angiotensinogen
D. Cortisol
C. Angiotensinogen
slide 13
What is the order of primary hemostasis and initial clot formation?
A. Subendothelial exposure → Activation → Adhesion → Aggregation → Platelet plug formation → Clot retraction/dissolution
B. Subendothelial exposure → Adhesion → Activation → Aggregation → Platelet plug formation → Clot retraction/dissolution
C. Adhesion → Subendothelial exposure → Activation → Platelet plug formation → Aggregation → Clot retraction/dissolution
D. Subendothelial exposure → Adhesion → Aggregation → Activation → Platelet plug formation → Clot retraction/dissolution
B. Subendothelial exposure → Adhesion → Activation → Aggregation → Platelet plug formation → Clot retraction/dissolution
Which of the following is an example of negative feedback?
A. High thyroid hormone levels suppress TSH release from the pituitary
B. Oxytocin release during childbirth increases contractions
C. Positive glucose uptake by insulin
D. Epinephrine stimulating heart rate during stress
A. High thyroid hormone levels suppress TSH release from the pituitary
Which gland stores and releases ADH and oxytocin?
A. Anterior pituitary
B. Posterior pituitary
C. Hypothalamus
D. Adrenal cortex
B. Posterior pituitary
endocrine physiology slide 14
Why is TSH considered a tropic hormone?
A. It only has endocrine function
B. It binds to receptors in and on the target organ
C. It regulates the production and secretion of other hormones
D. It is non-polar
C. It regulates the production and secretion of other hormones
endocrine physiology slide 5
What is the primary effect of angiotensin II?
A. Decreases blood pressure
B. Causes vasodilation
C. Vasoconstriction of arterioles and aldosterone release
D. Reduces sodium reabsorption
C. Vasoconstriction of arterioles and aldosterone release
hormones #2 slide 13
Which of the following is a major regulatory factor that prevents excessive clot formation?
A. Thrombin
B. Antithrombin
C. Fibrinogen
D. Factor VIII
B. Antithrombin
slide 23
In the hypothalamic–pituitary–adrenal (HPA) axis, which hormone provides negative feedback to the hypothalamus and pituitary?
A. Cortisol
B. ACTH
C. CRH
D. Aldosterone
A. Cortisol
endocrine physiology slide 18
What is the result when target cells down regulate?
A. Target cell becomes more sensitive to hormone
B. Hormone secretion increases
C. Exhibit fewer receptors
D. The cell produces more hormone
C. Exhibit fewer receptors
endocrine physiology slide 11
Thyroid hormone is an example of what type of hormone?
A. Polar
B. Cholesterol derived
C. Non-polar
D. Steroid hormone
C. Non-polar
slide 7
What is the most likely diagnosis for a patient who presents with hypertension, hypokalemia/renal potassium wasting, neuromuscular manifestations, and hypervolemia?
A. Addison disease
B. Cushing syndrome
C. Congenital adrenal hyperplasia
D. Hyperaldosteronism
D. Hyperaldosteronism
alterations in the endocrine system slide 17
What factor activates the intrinsic pathway?
A. von Willebrand factor
B. Factor II
C. Factor X
D. Factor XII
D. Factor XII
slide 23
What is an example of a negative feedback loop in the digestive system?
A. High stomach acid (HCl) inhibits gastrin release from the stomach
B. Stretching of the stomach wall during eating triggers hunger signals
C. Cholecystokinin (CCK) stimulates bile release from the gallbladder
D. Saliva secretion increases when you see food
A. High stomach acid (HCl) inhibits gastrin release from the stomach
digestive physiology slide 18
Which statement is true?
A. Lipophilic hormones bind to receptors on target organs
B. Lipophilic hormones bind to receptors in target organs
C. Lipophilic hormones bind to receptors in and on target organs
D. Lipophilic hormones bind to receptors around target organs
B. Lipophilic hormones bind to receptors in target organs
endocrine physiology slide 6
What is not a function of the thyroid hormone?
A. Contributes to calcium metabolism
B. Increases heart rate and contraction
C. Increases target cell responsiveness to catecholamines
D. Regulates basal metabolic rate
A. Contributes to calcium metabolism
slide 25
Which gland releases aldosterone during activation of the RAAS?
A. Thyroid gland
B. Pituitary gland
C. Adrenal cortex
D. Pancreas
C. Adrenal cortex
slide 12