aa side chain modifications
Number of times lysin can be methylated
3
DNA elements that make up the largest % of the human genome
LINEs
Pathways that can be involved in repairing stalled replication forks
NER, BER
Heterochromatin is highly condensed and associated with active transcription
False. Heterochromatin restricts transcription from taking place since it is highly condensed.
Chromatin that allows gene transcription
Euchromatin
Modification that adds a negative charge to a histone
phosphorylation
DNA region that prevents heterochromatin from spreading to active genes
Barrier DNA
Holliday junction
Barrier DNA prevents the spreading of heterochromatin
True
Stabilizes zigzag chromatin fiber structure
Histone H1 and histone tail interactions
Effect that acetylation of lysine has on histones
Removes positive charge, loosens chromatin
HMTs
adds methyl groups to lysine residues
Process that can cause gene conversion
homology-directed repair
Chromatin remodelers use GTP hydrolysis to reposition nucleosomes
False. Chromatin remodeling complexes use ATP hydrolysis to catalyze repositioning of nucleosomes.
Histone variant that replaces H3 at centromeres
CENP-A
Enzyme family that adds acetyl groups to histones
HATs
HDMs
removes methyl groups from histones
The main function of the FA pathway
Repair inter strand cross-links
Number of nucleosomes per ATP-dependent remodeling complex
5
Heterochromatin
highly compact, transcriptionally inactive chromatin
Enzyme family that removes acyl groups, promoting chromatin compaction
HDACs
Primary function of histone H1
Binds linker DNA to compact chromatin
Structure formed after strand invasion during HDR
D-loop
True
Reason why histone tails are intrinsically disordered
to interact with other proteins