DNA structure
what is all of the genetic information in an individual called?
Genome
T/F: okazaki fragments are only present on the leading strand
F
In what general phase can you start to see individual chromosomes?
Prophase
in what stage of the cell cycle are the proteins for mitosis synthesized?
G2
F
DNA wraps around what protein for packaging into nucleosomes?
Histones
DNA polymerase can only add nucleotides to what group?
3' hydroxyl
name the part of the cell cycle that differs between plant and animal cells
cytokinesis
P21 inhibits what kind of proteins?
name the type of stem cell that has lots of controversy around them
embryonic
the difference between deoxyribose and ribose sugars is the absence of what functional group?
Hydroxyl (OH)
in what phase of the cell cycle does DNA replication occur?
S phase
failure of the M checkpoint would most immediately impact what phase of mitosis?
anaphase
name 2 negative regulators of the cell cycle
P21, P53, Rb,
name the type of stem cell with the most differentiation potential
topipotent
why is it beneficial to have hydrogen bonds keeping the DNA double helix together?
bonds easily broken by helicase
What DNA replication enzyme is not activated in normal adult cells?
telomerase
name 2 things that happen in meiosis 1 that don't happen in meiosis 2
crossing over
formation of tetrads
separation of homologous chromosomes
reduction in ploidy
name 2 cell cycle control proteins that work together and explain their interaction
Rb/E2f
Rb/Cyclin-CDK
P53-P21
P21-Cyclin-CDK
name 1 difference between protoocnogenes and tumor supressor genes
+/- cell cycle control
Draw dATP (keep it SIMPLE)
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name an enzyme only found on the lagging strand of a DNA replication fork
Ligase
DNA polymerase δ
name the 3 ways meiosis increases genetic diversity
random fertilization
random assortment
crossing over
name 2 of the 3 major functions of p53
p21 (hault cell cycle)
repair
apoptosis
name 3 unique features of cancer cells
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