Sickle Cell Disease
This is the reason infants with sickle cell disease do NOT show symptoms until 3–4 months of age
What is the presence of fetal hemoglobin (HbF) that prevents sickling?
This blood-related complication is responsible for infection risk, bleeding, and anemia during radiation
What is myelosuppression/pancytopenia?
Children heal fractures faster than adults because of this anatomical structure
What is the thicker periosteum?
This medication category should be avoided in hemophilia patients due to bleeding risk
What are aspirin-containing products?
RBC transfusions help patients primarily by increasing this
What is oxygen-carrying capacity?
Dactylitis in sickle cell disease refers to this classic symptom
What is painful swelling of the hands and feet?
This syndrome causes excessive sleepiness in children receiving radiation
What is somnolence syndrome?
This leukemia type is more aggressive and often requires bone marrow transplant during remission
What is AML?
This treatment must be given IMMEDIATELY when a bleed occurs
What is factor replacement therapy?
Iron supplements should NOT be given with this beverage
What is milk?
This symptom results from rapid RBC turnover and increased bilirubin
What is jaundice?
List two short-term side effects involving the GI system
What are nausea/vomiting and mouth sores?
This leukemia type has the highest response rate to chemotherapy (90–95% remission)
What is ALL?
Describe correct care for a joint bleed (hemarthrosis)
What is ice, elevate, immobilize, NWB, and avoid PROM?
This action is strictly prohibited because it can be fatal during vesicant administration and lumbar puncture procedures
What is bringing a vesicant drug into the patient’s room during the LP?
Sickle cell disease causes these two long-term complications related to immune function
What are frequent infections and delayed growth?
This long-term endocrine effect can impact growth and sexual development
What is delayed or absent puberty?
This lab result is HIGH in early leukemia even though the cells are abnormal
What is elevated WBC with blasts?
Mouth bleeding in hemophilia is dangerous primarily because of this risk
What is airway obstruction?
Pancytopenia means a decrease in these three cell types
What are RBCs, WBCs, and platelets?
Explain why anemia occurs in sickle cell disease
What is chronic hemolysis caused by the destruction of sickled cells?
Radiation can cause this serious long-term effect involving the formation of new cancers
What are secondary malignancies?
The primary early intervention to prevent tumor lysis syndrome
What is aggressive IV hydration (1.5–2× maintenance)?
Hemophilia patients need this medication before and after dental work to prevent bleeding
What are antifibrinolytics?
This is the reason the nurse must leave the IV catheter in place during a suspected vesicant extravasation
What is to administer the antidote through the same line?