What are the 3 stages of cell signaling?
Receptor activation, signal transduction, and cellular response
what is the purpose of the signal transduction step of the cell signaling pathway?
what is to amplify a signal?
This scientist's X-RAY crystollagraphy helped determine DNA's 3D structure and their work got stolen
who is Rosalind Franklin?
what kind of signaling involves hormones like insulin and traveling long distances (ex: blood)
what is endocrine signaling
what is the role of secondary messengers in signal transduction?
what is to rapidly relay the signal?
Which scientists discovered that DNA was the transformational material?
Who are Avery, McCLeod, and McCarthy?
Quorum sensing is where bacteria send a signal but also have receptor for the same signal. Quorom sensing is an example of this type of signaling.
What is autocrine signaling?
what type of receptors can add a phosphate group?
enzyme linked
Who confirmed DNA was semi conservative ?
Who are Meselson and Stahl?
how do receptors activate after binding to a ligand
ligand binding to a receptor causes a change in shape of the INTRAcellular receptor
what is the common outcome of a KINASE cascade?
what is adding phosphate groups to proteins
Evan Chargaff measured amounts of A,T,G,C and found that amount of A=T and G=C. Would he have found this same result in RNA?
NO!
If a mutation in a G protein happened where the alpha subunit bonded more tightly to the beta gamma subunit, what would happen to the GPCR response?
mutation would inhibit the activation of the signal transduction pathway
In the lab, imagine you add a signaling molecule to a cell with NO surface proteins. The cell can still respond to the signal. How is this possible?
(Is the signaling molecule polar, non polar, and is the receptor extra or intracellular?)
Signaling Molecule is non polar and has an intracellular receptor