Lymphatic 1
What is the largest lymph node and it's function?
Spleen - filters blood
How are spleen and lymph nodes different?
Spleen filters blood and lymph nodes filter lymph
What is an antibody?
What are 3 possible nonspecific immune responses/defenses?
Fever, Inflammation, Phagocytosis, Parasite Killing, Apoptosis, Physical and chemical barriers
What is the force that drives fluid into lymphatic capillaries?
Hydrostatic pressure
How are primary and lymphatic structures differentiated?
Primary makes and matures cells. Secondary houses them and triggers immune response
A patient came with a parasitic infection. They completed a white blood count test. There should be an increase in what leukocyte?
Eosinophil
What cells act as APC?
Dendritic cells, Macrophages, B-Lymphocytes
What is an example of a lymphatic nodule?
Tonsils or MALT
Which lymphatic structure lacks a cortex and medulla?
Spleen
What are MHC molecules composed of and where are they formed?
Protein synthesized in the rough endoplasmic reticulum
What 2 cells perform apoptosis?
Natural Killer cell and Cytotoxic T-Cell
What body systems are supported by the lymphatic system?
Cardiovascular and immune
How does lymph return to the body's circulation?
Empties back into subclavian and jugular veins.
What are the benefits of fever?
Inhibit replication, Accelerate tissue repair, Increase CAMs, Promote immune response
What occurs during inflammation?
Vasodilation, Increase permeability, Recruit immune cells, and Increase fluid movement
How does the thymus tissue change with age?
When women with breast cancer undergo surgery to remove the tumor or the entire breast, the axillary lymph nodes are often removed as well. Why?
Axillary lymph nodes receive lymph from the breast and may house cancerous cells
What are the 3 actions of antibodies using antigen-binding site?
Neutralization, Agglutination, Precipitation
What would happen if T-lymphocytes that failed the negative selection test were not destroyed.
Develop an autoimmune disorder