Intracellular Transport
The methods of intracellular transport
BONUS POINTS (50): Match the organelle to the type of transport.
What is Pores (Nucleus), Translocators (ER & Mitochondria), and Transport Vesicles (ER & Golgi)?
The four types of Intermediate Filaments.
BONUS POINTS (50): The locations of each type.
What is keratin (cytoplasmic), lamins (nuclear), vimentin (cytoplasmic), and neurofilaments (cytoplasmic)?
The name of the checkpoint proteins
BONUS POINTS (50): Their function
What is cyclin (binds to CDK & oscillates) CDK (pushes from one phase to another by binding to cyclin)?
Examples of benign and malignant cancer cells (the names)
BONUS POINTS (50): Name all of them
What is benign: adenomas, meningiomas, and fibromas & malignant: sarcomas and carcinomas?
What is the trans-Golgi network, the compartments in Golgi (allow multiple vesicles to form), vesicles enter (coming from the ER), and vesicles exit/released?
The kDEL sequence
What is the ER retention signal; tells the retrieval vesicle to bring the protein back from Golgi to ER?
Example of MAP and what it does
What is TAU; stabilizes microtubules in an axon?
The difference between CDK+cyclin+(P) and CDK+cyclin
What is having a kinase phosphatase (needs step 2; remove phosphate from CDC 25 (WEE 1 inhibits CDK) to activate CDK+cyclin)?
Examples of tumor suppressor genes
What is APC & p53?
The two examples of motor proteins in nerve cells and the direction they go
What is kinesin (signals out) and dynein (signals in)?
The important components involved in intracellular transport in the mitochondria
What is chaperones, mitochondrial import receptor, mitochondrial sequence, translocator 1&2, signal peptidase, protein (aa chain), and the matrix?
The gamma-tubulin ring complex
What is where tubulin attaches and forms a microtubule (at the centrosome)?
The process of when a DSB occurs
What is first making p21 through p53 to bind to CDK complex to pause the cell cycle to rapid; can't repair=apoptosis through p53?
List all the key differences between normal and cancer cells
The two examples of actin in crawling (help retract & extend) & location
What is lamellipodium (knuckles) and filopodia (finger tips)?
Draw out and explain the RAN Cycle.
Professor Harris is the judge...
The three actin-binding proteins and their function
What is Thymosin (no to growth), Profilin (no to growth), and Formins (yes to growth/promotes polymerization)?
Full name for APC and function
What is anaphase-promoting complex that is involved with adding ubiquitination chains to promote degradation?
Potential causes of cancer
The range of aa sequences involved in NPC
What is 3-60 aa?
Draw out and explain budding & fusion, the example of an ER translocator, and the process involving dynamin.
Professor Harris is the judge...
Draw out the treadmilling process
Professor Harris will be the judge...
Purpose of the G1 phase
What is the growth phase where DNA must be correct (having no mutations), and produces a variety of proteins to continue to S Phase?
The full name for APC and its function
BONUS POINTS (150): explain the entire process of colon cancer by drawing it out & what is WNT
What is Adenomatous Polyposis Coli and a brake pedal in cell proliferation for WNT?
Professor Harris will be the judge of the drawing
Professor Harris' office hours location and where he actually has office hours
BONUS POINTS (150): days and times
What is Aliso Hall 201 and the SUB?
BONUS: Monday's & Friday's @ 9-10 AM