Oral Immune Responses
In the oral cavity, sIgA assists in the adherence of microbes to the oral epithelium. T or F?
What is False
Stimulation of RANK on ________ by RANKL triggers bone resorption.
What are osteoclasts?
T or F - Secondary immunodeficiencies are less common than primary immunodeficiencies.
What is false?
The primary mediator of type I hypersensitivity.
What is IgE?
Specialized antigen-presenting cells involved in contact-hypersensitive reaction in the skin.
What are Langerhans cells?
Saliva contains __________ which provides a physical and chemical barrier.
What are mucins?
Stimulation of RANK on ________ by RANKL triggers bone formation.
What are osteoblasts?
The type of immunodeficiency which is genetic.
What are primary immunodeficiencies?
The molecule that causes vasodilation following a type I hypersensitivity reaction.
What is Histamine?
Type IV hypersensitivity is also known as __________.
What is delayed hypersensitivity?
Saliva contains _____________ which have a biological effect by inhibiting the binding of microbes to the mucosal and tooth surfaces.
What are antibodies?
__________ competes with RANK for binding to RANKL.
What is osteoprotegerin?
X-linked severe combined immunodeficiency is the result of a mutation in IL2R common gamma chain and results in developmental defects in which two cell type(s)?
What are T cells and NK cells?
T cells are the immune cell type which causes anaphylactic shock. T or F?
What is false?
Cells that are involved in the induction of tissue damage as a result of Type III hypersensitivity.
What are neutrophils?
Oral epithelial cells produce the antimicrobial peptides known as __________.
What are defensins?
A serious direct consequence of a tooth extraction in individuals taking medicine such as Zometa (Zoledronate).
What is Medicine-Related Osteonecrosis of the Jaw?
The function of Nuclear Factor Kappa B (NF kappa B).
What is transcription of DNA?
The primary inflammatory mediator in Arthus reaction.
What is the classical complement pathway?
The most significant Th1 mediator causing delayed type hypersensitivity (DTH).
What is IFN gamma?
Within the gingival sulcus chemokines and adhesion molecules allow for continuous trafficking of leukocytes of which 98% are ____________.
What are neutrophils?
T or F - Osteoprotegerin inhibits bone resorption.
What is True?
An approach used as supportive therapy for individuals with primary immunodeficiency.
What is immunoglobulin transfer or prophylactic antibiotics?
Type II hypersensitivity reactions are mediated by _____ or _____ antibodies.
What are IgG and IgM?
The infiltrating immune cells most represented in a delayed hypersensitivity reaction.
What are helper T cells and macrophages?