This neurotransmitter inhibits aggression in humans.
What is serotonin?
100
State Hebb's rule.
"Neurons that fire together wire together."
100
This test is used to measure hypersecretion of cortisol in depressed patients.
What is dexamethasone or dexamethasone suppression test?
100
Name a negative symptom of schizophrenia.
What is impaired attention, difficulty problem solving, anhedonia, passivity, social withdrawal, impaired speech, blunted affect.
100
Name 2 characteristics of NMDA receptors.
Sensitive to glutamate, control Ca2+ channels, blocked by Mg2+, necessary for LTP, is a "molecular coincidence detector."
200
This hormone is necessary for male aggression.
What is testosterone?
200
NMDA receptors and Calcium help to: (Name 1 of 3).
Increase # of new AMPA receptors, creation of new synapses, make AMPA receptors more sensitive to glutamate.
200
Long-term antidepressant use can result in proliferation of neurons in the...
What is the hippocampus?
200
Many of the drugs used to treat schizophrenia inhibit....
What is dopamine or dopamine receptors?
200
Why is the NMDA receptor called a "molecular coincidence detector?"
Glutamate must be present, and the postsynaptic membrane must be slightly depolarized. Now, Mg2+ is removed and Ca+ can enter its channel.
300
Name one effect of stress discussed in class.
Impair immune system, impair reproduction, impair growth, decrease digestion, increase fear and anxiety,
300
This ion must be removed from the NMDA receptor in order for LTP to occur.
What is magnesium?
300
This antidepressant has many dietary restrictions.
What are MAOIs?
300
The positive symptoms of schizophrenia are the result of....
What is an overactive dopaminergic system?
300
This disorder is associated with decreased hippocampal volume.
What is depression?
400
Low levels of this metabolite has been associated with anti-social behavior in humans.
What is 5-HIAA?
400
Influx of this ion into the neuron through its channel located in the NMDA receptor is necessary for LTP.
What is Ca2+?
400
List the 4 classes of drugs used to treat the symptoms of depression.
What are MAOIs, SSRIs, TCAs, Atypical or 3rd generation?
400
Name one explanation for the development of negative symptoms associated with schizophrenia.
What is brain damage (enlarged ventricles, disorganized hippocampus, cerebral atrophy), PFC hypofrontality, NMDA dysregulation.
400
This type of drug would be used to treat Generalized Anxiety Disorder (GAD).
What is a GABA agonist (benzodiazepine)?
500
This disorder has high comorbidity with depression.
What is Generalized anxiety disorder (GAD)?
500
Classical Conditioning: You eat a new food and then get sick because of the flu. However, you develop a dislike for the food and feel nauseated whenever you smell it.
The flu sickness is the US.
The nausea is the UR.
The new food is the CS.
The nausea to the new food is the CR.
500
Name 2 criticisms of the Monoamine Hypothesis of depression.
What is too simplistic, no direct relationship, measurement of amines, cocaine, delayed therapeutic effect.
500
These antipsychotics reduce the negative symptoms of schizophrenia.
What are atypical or 2nd generation antipsychotics?
500
This disorder is considered the most debilitating of all mental disorders.