ABO
What type of testing does the BB perform when determining the blood group of a patient?
Phenotyping
If a patient has a positive DAT, should you perform a weak D test on the cells?
No, the cells are already coated with antibody
What should be done with a donor unit that has a positive DAT?
With EXM's you will never know if you have given a unit with a positive DAT.
But, once it is seen it can't be unseen. Discard the unit.
What is the most common antibody seen in the blood bank after ABO and Rh antibodies?
Anti-K
When no clinically significant unexpected antibodies are detected in the patient’s plasma and there are no records of previous detection of such antibodies, what is the minimum crossmatch testing required?
EXM or IS XM
Wehn a patient's sample shows a discrepancy between forward and reverse grouping with missing or weak reactions, what can be done to enhance these reactions?
Incubate 15-30 minutes at room temperature or 4 degrees.
Select a donor for a recipient with anti-c:
r'r
R0R1
R2r'
r'ry
r'ry
Polyspecific AHG contains?
Anti-IgG and anti-C3d
Which blood group system is associated with resistance to P. vivax?
Duffy
How long must a recipient’s blood specimen be retained following transfusion?
7 days
What group am I?
Anti-A: 0
Anti-B: 0
Anti-D: 3+
A1 Cells: 4+
B Cells: 4+
Group O
Which genotype is capable of making an Anti-C?
R1r
R1R1
r'r
rr
rr
Why are IgG Sensitized Cells (Check Cells) added to all negative reactions in the AHG test?
To ensure AHG was not neutralized by free globulin molecules
Name a blood group that is known for causing dosage?
Duffy
Kidd
MNS
Rh
What is the minimum information required on a blood sample for pre-transfusion testing?
Two unique patient identifiers must be on tube. Collector, D/T of Collection must be retrievable.
Forward grouping is defined as:
Detection of ABO Antigens on a Patient’s Red Blood Cells by using Antisera.
Which genotype could show dosage for C?
dce/dce
dCE/dCE
DCE/DCE
DCe/DcE
DCe/DcE
An antibody screen is being performed, and all three tubes are negative after adding AHG. Check cells are added and the tubes are centrifuged. No agglutination occurs after the addition of check cells. What is the next course of action?
Repeat the antibody screen
The most clinically significant blood group antibodies are which class of Ig?
IgG
Today is June 8, 2016. What is the earliest date of collection in which the samples could still be used for pretransfusion testing in a patient with a history of red blood cell transfusion 82 days ago?
June 5, 2016
What substance must be formed first before A or B specificity is determined?
H
Biochemically, what type of molecules are the Rh Antigens?
Proteins
What is the main purpose of the antiglobulin test?
To detect patient red cells coated with antibody or complement
What is the pattern of reactivity you would expect to see in the Donath-Landsteiner test for a patient that is suspected of paroxysmal cold hemoglobinuria?
Antibody attaches to RBCs at 4 degrees and causes hemolysis at 37 degrees.
As a safety measure, blood banks are required to compare a patient’s previous and current records / results. Which of the following is a required component of the comparison process?
Historical ABORh type