Renal Pharmacology
In the setting of persistent renal hypoperfusion despite fluid resuscitation, vasoactive agents are used to achieve this MAP goal.
What is 65mmHg?
The milliliters of antithrombin (Thrombate III) needed for a dose of 1795 IU.
What is 36mL?
The distribution of water in the extracellular space.
What is 1/4 plasma and 3/4 interstitial?
According to Bronsted-Lowry, this compound accepts a proton
What is a base?
Phentolamine is FDA approved for the management of this medical condition
What is extravasation?
Paradoxical hypercarbia is a known adverse drug reaction of this alkalinization agent?
What is sodium bicarbonate?
A functional assay
What is serotonin release assay (SRA)?
Normal range for osmolarity
What is 275-295 mOsm/L?
Molecules or ions that can act as both an acid and base in chemical reactions
What are amphoteric compounds?
The name commonly used when referring to norepinephrine
What is Levophed?
Na+ - (Cl- + HCO3-) is the equation to calculate this measurement.
What is anion gap?
This is the pump, loading and continuous infusion dose of bivalirudin for CPB
What is 50mg for pump prime, 1 mg/kg for loading dose, and 2.5 mg/kg/hr?
It is the most abundant extracellular electrolyte
What is sodium?
In this equation, what is KOH when added to water:
KOH (aq) + H2O (l) → K+ (aq) + OH- (aq)
What is a strong base?
Some patients require short term use of insulin when receiving this medication
What is epinephrine?
These products are NOT commended for fluid resuscitation given the risk for renal dysfunction and need for renal replacement therapy (RRT).
What are semisynthetic colloids?
This is an alternative product used to increase antithrombin levels with Thrombate III is unavailable
What is fresh frozen plasma?
In this reaction, H3PO4 is functioning as this type of electrolyte
H3PO4 -> H3O+ + H2PO4-
What is a weak electrolyte?
This is the natural buffer system in humans
What is the carbonic acid-bicarbonate ion buffer system?
This is the preferred vasopressor to use for managing hypotension in patients with concomitant pulmonary hypertension
What is vasopressin?
This BUN:SCr ratio is indicative of pre-renal azotemia.
What is >20:1?
These are the 4 Ts in the 4T Scoring System
What are thrombocytopenia, timing of thrombocytopenia, thrombosis, and other causes of thrombocytopenia?
Hemolysis can occur from the improper infusion of this fluid
What is hypotonic fluid?
In this equation, NH4+ is this type of acid
HCl (aq) + NH3 (aq) → NH4+ (aq) + Cl- (aq)
What is a conjugate acid?
This pure alpha-1 agonist ↓ venous capacitance → ↑ cardiac preload and stroke volume
What is phenylephrine?