Rheum
Name That Mass
Psych-Neuro
Renal
Autonomic
100

This vasculitis in children may cause coronary artery aneurysms

What is Kawasaki disease?


100

This primary cardiac tumor constitutes 50% of all benign cardiac tumors in adults

What is myxoma?

80% LA, can be seen in any chamber

100

After an angry outburst, the risk of acute myocardial infarction increases within this short time window

What is 2 hours?


  • 1994 Northridge earthquake (Los Angeles)

    • MI: ↑ 35%

    • Sudden cardiac death: 4.6/day → 24/day

  • 1995 Great Hanshin (Kobe) earthquake

    • MI: ↑ 3.5-fold

    • Fatal MI: ↑ (significant increase)

  • 1989 Loma Prieta earthquake

    • MI: no increase

  • 1991 Persian Gulf War (missile attacks on Israel)

    • CV mortality: ↑ 58% (day 1)

  • September 11, 2001 (New York City)

    • CV mortality: no increase

  • Bereavement (death of a child – Danish study)

    • First MI: ↑ 31%

    • Fatal MI: ↑ 58%

  • Death of a loved one (Determinants of MI Onset Study)

    • MI risk: ↑ 21-fold

  • Bereavement (UK primary care study, 30-day outcomes)

    • MI: rate ratio 2.14

    • Stroke: rate ratio 2.40


100

This process is accelerated in CKD and contributes to CAD, valvular disease, and arrhythmias

 What is (medial) calcification?


100

In a denervated heart, this happens to heart rate (increase vs decrease)

Increase. Sinus normally runs >100 bpm, parasympathetic input dominates

200

In patients <40 years old, these red flags may be related to Takayasu arteritis (count 2)


TABLE 97.3


“Red Flags” for Takayasu Arteritis

In patients younger than 40 years the following may indicative of TA:

Unexplained acute-phase response (raised ESR and/or CRP)

Carotidynia

Hypertension

Discrepant blood pressure between the arms (>10 mm Hg)

Absent/weak peripheral pulse or pulses

Limb claudication

Arterial bruit

Angina



TABLE 97.2


Cardiovascular Disease in the Systemic Vasculitides

Vasculitides    Cardiovascular Complications

Large-Vessel Vasculitis

Giant cell arteritis    Thoracic/abdominal artery aneurysm, limb ischemia, pericarditis, coronary arteritis, IHD, MI

Takayasu arteritis    Aortic regurgitation, limb ischemia, aortic stenosis, aortic aneurysm, stroke, hypertension, coronary arteritis and aneurysm, IHD, MI, myocarditis, cardiac failure

Kawasaki disease    Coronary artery aneurysm, MI, myocarditis, pericarditis, valvular dysfunction, cardiac failure

Medium-Vessel Vasculitis

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)    Myocarditis, pericarditis, coronary arteritis, cardiomyopathy, cardiac fibrosis, valvular dysfunction, MI

Polyarteritis nodosa    Myocarditis, pericarditis, coronary arteritis, coronary aneurysm, hypertension, cardiac failure

Wegener granulomatosis (granulomatous polyangiitis)    Myocarditis, pericarditis, coronary arteritis, valvular heart disease, cardiac failure

Microscopic polyangiitis    Pericarditis, coronary microaneurysm, MI

200

48 year old woman with breast cancer - suggestive of

What is catheter related thrombus?

No LGE

200

This genetic muscle disease primarily affects the posterior wall initially, can cause tall R waves in V1

What is Duchenne's MD?

200

This urine test (with a threshold of 30–300 mg/g) defines microalbuminuria and independently predicts cardiovascular risk.

What is albumin-to-creatinine ratio (ACR)?

200

This diagnosis is defined by a resting sinus rate over 100 bpm, or an average Holter rate over 90 bpm, without a reversible cause.

What is inappropriate sinus tachycardia (IST)?

300

This vasculitis with a prodrome of allergic rhinitis, sinusitis, asthma precedes cardiac involvement (up to 60% of cases)

What is EGPA (Churg Strauss)?

pericarditis, myocarditis, coronary arteritis, myocardial infarction, cardiac fibrosis, arterial thrombosis, and valvular dysfunction. Cardiac disease is a prominent cause of death. 


300

This is an autosomal-dominant condition associated with cardiac myxomas, myxomas in other regions (cutaneous or mammary), hyperpigmented skin lesions, hyperactivity of the adrenal or testicular glands, and pituitary tumors

What is Carney Complex?

Younger age, multiple myxomas

300

This personality type, combining negative affectivity and social inhibition, has been linked to worse cardiovascular outcomes.

What is Type D personality?


300

This inotrope dose needs to be adjusted to kidney function, avoided in CKD 5/ESRD

What is milrinone?

300

This ablation aims for gangilonated plexi for vasovagal syncope

What is cardioneuroablation?

400

This endocarditis type happens in SLE patients, commonly with bilateral mitral leaflet involvement and negative blood cultures

What is Libman-Sacks endocarditis? (verrucous endocarditis)



400

This diagnosis is associated with malignancies, give a possible symptom

What is SVC syndrome? Stenting. Head fullness, arm swelling, redness

400

This SSRI prolongs QTc the most in a dose dependent fashion

What is citalopram?

400

After many small, suggestive studies, a large (n = 2308) randomized trial of this medication showed no differences in the rates of contrast induced AKI (12.7% for both groups), ESRD, or other outcomes

What is N-acetylcysteine 1200 mg p.o. bid the day before and after the procedure?

400

This bedside procedure targets the stellate ganglion with local anesthetic in the supraclavicular region and can suppress refractory ventricular arrhythmias.

This surgical treatment removes the lower stellate ganglion and T2–T4 ganglia and is used for refractory VT/VF, long QT syndrome, and catecholaminergic VT.

What is stellate ganglion block?

What is cardiac sympathetic denervation? 




500

This vasculitis with uveitis, genital and oral ulcers may cause pulmonary artery aneurysms

What is Behcet's disease?



500

In children, this is the most common benign cardiac tumor and is strongly associated with tuberous sclerosis

What is a rhabdomyoma?


500

This specific ventricular tachycardia mechanism seen in myotonic dystrophy originates from the His-Purkinje system.

 

What is bundle branch reentry tachycardia?


500

2/4 of these antiarrhythmics needs to be renally dosed

Amiodarone, Dofetilide, Sotalol, Dronaderone

What is Dofetilide and Sotalol?

  • Amiodarone → No dose adjustment

  • Dronedarone → No dose adjustment

  • Dofetilide →

    • CrCl >60 → 500 mcg BID

    • CrCl 40–60 → 250 mcg BID

    • CrCl 20–39 → 125 mcg BID

    • CrCl <20 → ❌ Contraindicated

  • Sotalol →

    • CrCl 30–59 → Dose q24h

    • CrCl 10–29 → Dose q36–48h

    • CrCl <10 → Individualize


500

The diagnosis in this tilt table test

What is POTS?

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