Anything Goes
Surprise Surprise
100

This systemic fungal infection caused by inhalation of airborne spores from the soil-dwelling fungi which are endemic to arid regions of the southwestern United States, Mexico, and parts of Central and South America. Please spell out this condition, also known as Valley Fever.

What is COCCIDIOIMYCOSIS?

100

The presence of this specific autoantibody subtype in a mother’s serum has been strongly linked to the development of fetal or neonatal complete heart block, even in the absence of classic lupus or Sjögren’s features.

What is Anti Rho-52 antibody?

200

According to USPSTF guidelines, this cancer screening should begin every 2 years starting at age 40 for average-risk women. 

What is breast cancer screening (mammogram)?

200

This adult onset disease is associated with specific autoantibodies that contribute to characteristic "mechanic hands" and interstitial lung disease. 

What are Anti–Jo-1 and Anti–Mi-2 antibodies?

(Adult Onset Dermatomyositis)

300

When your patient shows up with painful buboes, sepsis, and a history of handling prairie dogs, suspect this safety pin–shaped, bipolar-staining bacillus carried by fleas.

What is Yersinia pestis? 

300

This tyrosine kinase inhibitor revolutionized cancer treatment by targeting the BCR-ABL fusion protein in chronic myeloid leukemia, and it’s also the go-to therapy for GIST tumors with KIT (CD117) mutations.

What is Imatinib?

400

This hyperinflammatory syndrome is characterized by persistent fever, hepatosplenomegaly, cytopenias, coagulopathy, transaminitis, hypertriglyceridemia, hypofibrinogenemia, and extreme hyperferritinemia (>10,000). Biopsy often reveals hemophagocytosis in bone marrow or spleen. 

What is Hemophagocytic Lymphohistiocytosis?

400

Developed to treat atrial fibrillation, this surgical procedure creates a series of precisely placed atrial incisions or ablations that direct electrical impulses through a controlled pathway

What is the MAZE procedure?

500

This fibroinflammatory condition can mimic malignancy or infection in nearly any organ, from the pancreas and salivary glands to the aorta and kidneys, and is characterized by storiform fibrosis, obliterative phlebitis, and infiltration with plasma cells.

What is IgG4 Related Disease?

500

This corneal infection presents with pain, photophobia, and decreased vision. Fluorescein staining reveals the classic branching “dendritic” ulcer

What is herpes simplex keratitis

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