Molecular and Cellular Basis of Disease / Clinical Case
The name of today's lecturer
Who is Peter Novick?
The powerhouse of the cell
What is mitochondria?
These organelles function in intracellular digestion/degradation
What is lysosomes?
Structures like cilia and flagella in respiratory tissue and sperm cells are specialized for this function
What is motility?
(movement/transport also accepted)
The basic building blocks of life. Arranged into tissues to form organs
True or False: There is no treatment for Tay-Sachs Disease.
True
Genetic structures that become visible when a cell is about to divide
What is chromosomes?
The cell membrane is constructed of a __________ bilayer with hydrophilic, outward-facing heads and hydrophobic inner tails
What is phospholipid?
A tissue type or organ that uses secretory cells
- Pancreas
- Adrenal Gland
- Respiratory tissue
- Intestinal tissue
- Mucous membranes
- Parietal cells (stomach)
These cells appear throughout the gut epithelium and secrete mucus
What are goblet cells?
What is cell?
Name a component of the cytoskeleton (there are 3 options covered in lecture)
What are actin filaments/microtubules/intermediate filaments?
(microfilaments are another accepted name for actin filaments)
This organelle synthesizes proteins and most lipids in the cell
Endoplasmic reticulum (ER)
Endothelial cells form the lining of these structures
What is
- capillaries
- arteries
- veins
+100 for each correct
This tissue type lies between the epithelium and smooth muscle in the small intestine
What is connective tissue?
"All ______ are reducible to active or passive disturbances in the cell."
What is diseases?
The mitochondrion and the _______ are the only two organelles in animal cells with a double membrane.
What is the nucleus?
This organelle modifies, sorts, and packages proteins and lipids for secretion or delivery to another cell
What is the Golgi (apparatus/body/complex)?
These structures on the intestinal epithelium create the "brush border" of the intestinal lumen, greatly increasing surface area available for absorption
What are microvilli?
In humans, ciliated epithelium is found in this structure
What is the trachea?
(also accept bronchial tubes, nasal passages)
Tay-Sachs Disease, whose symptoms include (), is caused by issues with this organelle
- seizures
- behavior changes
- listlessness
- delay/loss of motor, social, intellectual skills
- feeding difficulties
What are lysosomes?
Ribosomes, tiny protein-synthesizing organelles, float freely in the cytoplasm or are attached to the ______________
What is the ER (membrane)?
These organelles carry out oxidation of toxic molecules
What is peroxisomes?
This word describes epithelial cells that feature different structures on one end than the other, such as intestinal lumen cells specialized for absorption
What is polarized?
The highest possible score on the MCAT
What is 528?