Blood Bank Testing
This class of antibody is the best at binding complement and reacts mainly at room temperature
IgM
The sugar that makes up the A antigen
N-Acetylgalactosamine
This antigen or antigens is build off of the H antigen
A and B antigens
The most common typing discrepancy
Weak/missing back type
The percentage of people with blood type A that are from the A2 subgroup
20%
This term describes the half of blood typing where the patient's plasma is combined with reagent red cells to identify any ABO antibodies present
Back/reverse type
The blood type that is most prevalent across all populations
Type O
The blood type with the least amount of exposed H antigen
A1B
In gel testing, this discrepancy is caused by multiple red cell populations in the patient sample
Mixed-field
The plant that anti-A1 lectin is derived from
Dolichos biflorus
The purpose of a control well/tube in the front type is to detect what?
Spontaneous agglutination/panagglutination
The Anti-A and/or Anti-B produced by humans belongs to what antibody class(es)?
Majority IgM, some IgG
On red cells, the H antigen is added to what structure?
The Type 2 oligosaccharide precursor chain
Patients with an ABO discrepancy that cannot be resolved can only get this type of red cells with this type of testing
Immediate spin crossmatch with Type O RBCs
This A subgroup tends to display results that appear to be mixed field in the front type
A3
How should an antibody screen performed via solid phase testing with an intact cell button at the bottom of the well be interpreted?
Negative
The universal recipient for plasma
Type O
A recessive genotype that results in the lack of this direct gene product is what causes the Bombay phenotype
L-fucosyltransferase
Causes discrepant results in both the front and back type and can be resolved by washing the red cells and saline replacement respectively
Rouleaux
This reagent may produce stronger reactions with the A3 and Ax subgroups than The standard Anti-A reagent
Anti-A,B
This category of testing includes antibody screens, panels, weak D, and full/extended crossmatch
Indirect Antiglobulin Test (IAT)
Explain how 2 parents with the blood types A and B can produce a Type O child
Their genetics are AO and BO
The ABO discrepancy(ies) Bombay individuals tend to display
None
The antigen produced in the acquired B discrepancy requires what substance to be deacetylated into what?
N-Acetylgalactosamine into D-galactosamine
The Anti-A1 antibody belongs to this class of antibody and is usually formed in this way
Inherent IgM made without exposure