Pathophysiology
A patient presents with acute monoarticular joint pain in the great toe. Which pathophysiologic mechanism best explains the sudden onset?
What is deposition of monosodium urate crystals after purine overload
Which medication is most appropriate for acute gout with renal impairment?
What is low-dose colchicine
Positive McMurray test suggests injury to what structure?
What is Meniscus
Which imaging is best initial test for suspected fracture?
What is X-ray
First-line treatment for acute low back pain without red flags is:
NSAIDs and activity
A 68-year-old develops vertebral compression fractures. Which mechanism is most responsible?
What is increased osteoclast-mediated bone resorption
A patient on long-term steroids is at risk for osteoporosis. Which drug prevents this?
What is Teriparatide
Straight leg raise reproduces pain. What does this indicate?
What is Lumbar radiculopathy
Elevated ESR and CRP most strongly suggest what?
What is inflammatory process
A patient with RA flare should receive:
What is a Short steroid burst
A patient with septic arthritis develops rapid joint destruction. Which process drives this?
What is proteolytic enzyme release from neutrophils
Which medication requires renal adjustment in elderly patients?
What is Naproxen
A patient has Heberden nodes. What is this associated with?
What is OA
Synovial fluid with >50,000 WBC suggests:
What is Septic arthritis
Which lifestyle change helps osteoporosis?
What is Weight-bearing exercise
In rheumatoid arthritis, what best explains morning stiffness?
What is cytokine-driven synovial inflammation
Which drug class slows RA progression?
What is DMARDs
Positive Phalen test indicates compression of which nerve?
What is Median nerve
DEXA scan T-score of –2.8 indicates:
What is Osteoporosis
For suspected septic arthritis, initial step is:
What is Joint aspiration
A runner develops stress fractures. What mechanism is the primary cause?
What is insufficient bone remodeling time
Which medication is contraindicated with peptic ulcer disease?
What is Naproxen
Trendelenburg gait suggests weakness of which muscle?
What is Gluteus medius
MRI is most useful for evaluating:
What is Soft tissue injury
Best choice for chronic OA knee pain refractory to NSAIDs:
What is Steroid injection