How long does it take for an allergic reaction to begin after exposure?
Minutes to 2 hours
Which foods most commonly cause anaphylaxis in the United States? Name 2
Peanuts/tree nuts (walnuts, pecans, pistachios, cashews)
Shellfish (crustaceans and mollusks) and fish
Can also include:
Milk, egg, sesame
Chronic diarrhea, anorexia, abdominal distension/pain, failure to thrive, weight loss, signs of nutrient deficiency d/t malabsorption, flatulence. Kids/adolescents
Celiac disease
Most common cutaneous manifestations of allergic reactions to food (name 1)
Urticaria and angioedema. May also accept pruritis.
What is Ravneet's dog's name?
Bumi
Name the immunoglobulin and the 2 cell types that are involved in type I reactions
IgE
Mast cells
Basophils
List at least 2 GI symptoms that occur in allergies/anaphylaxis
Abdominal cramping
Diarrhea
Pollen-food allergy, symptoms usually limited to the oropharynx
Oral allergy syndrome. Reactions are typically to fresh/raw foods, not cooked
Contact dermatitis
Who/what is Ravneet's dog named after?
Character from Avatar the last airbender
T-cell mediated immune reaction
Type IV
Children with meat allergy often have atopic dermatitis and may present with asthma, pruritis, and urticaria. Name some meats that most commonly cause IgE-mediated allergic reactions (need 1 of 3)
Beef
Lamb
Pork
Dysphagia, vomiting, abdominal pain, history of food impaction, failure to respond to antacids and antireflux therapies. Can be caused by cow's milk, egg, soy, corn, wheat, beef
Eosinophilic esophagitis
Classic skin rash of gluten-sensitive enteropathy and where does it occur
Dermatitis herpetiformis; extensor surfaces
When Ravneet was a kid, what organized afterschool activity did she participate in?
Ballet and tap
Drug immune complex deposition and complement activation, caused by IgG
Type III
Viral infections that can predispose patients to reactions to certain drugs (name 2)
HIV - bactrim
EBV - amoxicillin
CMV - abx
HHV6 - anticonvulsants
Systemic reaction that begins 1-12 weeks into continuous treatment with a drug. Fever, rash, multiorgan involvement. Can persist for weeks to months even after drug is stopped
DRESS: drug rash with eosinophilia and systemic symptoms
Name 2 medications that commonly cause type I drug reactions
Beta-lactams
Quinolones
Carboplatin
Rituximab
Name a country and 2 states Ravneet has visited
Canada, India, Ireland, Denmark
FL, MA, NY, NJ, MD, TN, MI, IL, IN, TX, CA, KS, MS
Drug-induced hemolytic anemia, thrombocytopenia, and neutropenia are examples of what immune response (type).
Type II
Medications that can cause a lupus-like disease (name 1)
Procainamide, Phenytoin, isoniazid, sulfasalazine, amiodarone, minocycline, penicillamine
Define Baker's asthma
IgE-mediated allergy to inhaled wheat protein. No reaction to the food upon ingestion.
Fever and mucocutaneous lesions, necrosis and sloughing of the epidermis
Steven Johnson syndrome
Allopurinol
Lamotrigine
Sulfasalazine
Nevirapine
NSAIDs
Before Ravneet became a premed, what was she planning to become?
A teacher (I would not have been good at that LOL)