Toxicology Basics
This term describes the amount of drug needed to cause a harmful effect.
What is Dose?
THC is the active compound in this drug.
What is cannabis/marijuana?
The best specimen for screening samples.
What is urine?
This term refers to the cause of death from excessive drug levels.
What is overdose?
This instrument separates volatile substances and uses a flame ionization detector.
What is GC-FID?
The study of how the body absorbs, distributes, metabolizes, and excretes drugs.
What is pharmacokinetics?
This class includes substances like heroin and morphine.
What are opioids?
Liquid portion of blood with electrolytes and coagulation proteins.
What is plasma?
Redistribution of drugs after death is known as this.
What is postmortem redistribution?
Compound chemically similar to your compound of interest used to determine analyte concentration.
What is internal standard?
This is the chemical property that describes a drug’s fat solubility.
What is lipophilicity?
Cocaine and amphetamines fall under this category.
What are stimulants?
Small amount of viscous fluid in an isolated area resistant to decay.
What is Vitreous Humor?
This is a preferred specimen for toxicological analysis in postmortem cases.
What is femoral blood?
Based on the transfer of a drug from one liquid phase into another liquid phase according to the solubility.
What is Liquid-Liquid Extraction?
The principle “the dose makes the poison” was coined by this father of toxicology.
Who is Paracelsus?
Benzodiazepines and ethanol belong to this drug class.
What are CNS depressants?
Biologic sample with a detection window of 5-48 hours of the parent compound.
What is oral fluid?
This pharmacokinetic factor contributes heavily to PMR.
What is volume of distribution?
Most common instrument used for confirmatory testing (full name).
What is Liquid Chromatograph Tandem Mass Spectrometer (LC/MS/MS).
The two preservatives present in grey top tubes.
What is Sodium Fluoride and Potassium Oxalate?
These drugs distort perception and include LSD and psilocybin.
What are hallucinogens?
Sample used to analyze pill fragments.
What is gastric contents?
The antemortem blood source.
What is cephalic vein?
Mixed mode solid phase extraction (SPE).
What is combination of reversed phase SPE and ion exchange?