Immune Concepts II
Hypersensitivity
Immuno- Potpourri
Bugs & Drugs
Viruses
100

The main function of lymph nodes in the immune system.

What is to serve as filters where immune cells encounter antigens?

100

This type of hypersensitivity is exemplified by serum sickness.

What is Type III hypersensitivity?

100

This cell directly destroys virus-infected cells through perforin and granzyme release.

What is a cytotoxic T cell?

100

This is the mechanism for bacterial resistance in Rifampin and other DNA/RNA inhibitors. 

What is mutation in RNA polymerase?

100

Varicella-zoster belongs to this virus family.

What is herpesviridae?

200

This cytokine type primarily promotes inflammation.

What is Tumor Necrosis Factor-alpha?

200

This immune mechanism underlies Type II hypersensitivity reactions.

What is antibody-mediated cytotoxicity?

200

This part of the antigen is recognized by an antibody.

What is the epitope?

200

Multidrug-resistant tuberculosis (MDR-TB) is defined by resistance to these two drugs.

What is isoniazid (INH) and rifampin?

200

Chronic infection is most commonly caused by this hepatitis virus.

What is HBV?

300

This is what pattern recognition receptors (PRRs) are responsible for.

What is detecting pathogen-associated molecular patterns?

300

This immunologic finding characterizes systemic lupus erythematosus.

What is immune complex deposition?

300

This antibody is mainly produced in a primary immune response.

What is IgM?

300

This is the target site for aminoglycoside antibiotics. 

What are ribosomes?

300

Viral families differ by replication enzyme requirements. Negative-sense RNA viruses must carry this.

What is RNA polymerase?

400

This complement pathway is activated directly by antibodies. 

What is the classical pathway?

400

This antibody mediates Type I hypersensitivity reactions. 

What is IgE?

400

For full T cell activation TCR-MHC binding and this signal is necessary.

What is co-stimulatory molecule interaction?

400

M protein is a virulence factor of this gram positive cocci.

What is Streptococcus pyogenes?

400

The goal of NRTIs is to inhibit this.

What is reverse transcriptase?

500

This is the description of passive immunity.

What is administration of pre-formed antibodies?

500

This is the underlying  immunologic process in contact dermatitis.

What is delayed T-cell medicated hypersensitivity?

500

This produces T cell receptor diversity.

What is recombination of V(D)J gene segments?

500

This color pigment is characteristically produced by Pseudomonas aeruginosa.

What is blue-green?

500
Hepatitis C virus (HCV) belongs to this virus family. 

What is flaviviridae?

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