Immune Concepts
APCs & MHCs
Vaccines
Antigens & Antibodies
Potpourri
100

The immune cell that is primarily responsible for engulfing and digesting pathogens.

What is a macrophage?

100

The function of MHC Class I molecules.

What is to present endogenous peptides to cytotoxic T cells?

100

This is the main goal of vaccination.

What is to generate immunologic memory?

100

This part of an antigen is recognized by an antibody. 

What is the epitope?

100

This antibody mediates Type I hypersensitivity reactions. 

What is IgE?

200

Where T cells undergo maturation.

What is the thymus?

200

This type of T cell recognizes peptides presented by MHC Class II molecules.

What are CD4+ helper T cells?

200


This type of vaccine uses a weakened form of the pathogen.

What is live-attenuated vaccine?

200

This antibody is primarily produced in a primary immune response. 

What is IgM?

200

Contact dermatitis results from this immunologic process. 

What is delayed T-cell mediated hypersensitivity?

300

The main consequence of a deficiency in the complement system. 

What is increased susceptibility to bacterial infections?

300

This cell directly destroys virus-infected cells through perforin and granzyme release. 

What is a cytotoxic T cell?

300

This is how herd immunity helps prevent infectious disease spread. 

What is by lowering the number of susceptible hosts?

300

This is where B-cell maturation begins.

What is bone marrow?

300

This is the main risk associated with prolonged immunosupression therpay. 

What is increased infection and malignancy risk?

400

The primary function of the immune system.

What is to protect the body against pathogens and foreign substances?

400

This is the main reason MHC compatibility is critical in transplantation.

What is because it ensures graft recognition as self?

400

This type of vaccine contains an inactivated toxin. 

What is toxoid vaccine?

400

This is the main function of plasma cells.

What is antibody secretion?

400

This type of immunodeficiency results from HIV infection. 

What is secondary acquired?

500

How innate and adaptive immunity differ.

What is Innate immunity provides non-specific defense, while adaptive immunity is specific

500

This happens if a T cell binds strongly enough to a self-antigen during negative selection. 

What is apoptosis?

500

This is the main purpose of booster vaccines.

What is to strengthen and prolong immune memory?

500

This immunoglobulin is most abundant in mucosal secretions. 

What is IgA?

500

This vaccine type contains only parts of a pathogen, such as proteins or polysaccharides.

What is a subunit vaccine?

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