H5N1 Paper
This animal model was used to test whether the mutated H5N1 virus could be transmitted through the air between individuals.
What is a ferret?
Research that involves giving an organism a new function
What is Gain of Function?
What administration was the first to introduce a moratorium for Gain-of-Function
What is Obama?
This lab studies salamanders.
What is Staub's Lab?
This protein, mutated at positions Q222L and G224S in the study, determines influenza virus binding to host cells.
What is hemagglutinin (HA)?
Three uses for GoF research on viruses and bacteria
What are vaccine development, understanding transmission, and drug target identification?
What year did President Trump terminate NIH funding for the EcoHealth Alliance’s collaboration with the Wuhan Institute of Virology?
What is 2020?
What is the highest BSL level lab on campus?
What is BSL-2?
The Herfst et al. study was conducted in this type of enhanced containment facility to safely study airborne-transmissible pathogens.
What is an ABSL3+ (enhanced Animal Biosafety Level 3) facility?
A human hormone we can commercially synthesize due to gain of function research
What is insulin?
When did the three year moratorium on funding gain-of-function research get put into place?
October, 2014.
Name 3 of the 5 lab classes that are part of the chalcone CURE PIPELINE.
O-CHEM I & II, Biochemistry, Advanced Cell, Microbiology?
This paper raised these kinds of ethical and safety concerns.
What are biosafety and biosecurity concerns (or gain-of-function research risks)?
An agricultural discovery made by Gain of Function research
What is modification of rice plants to be resistant to climate change?
What category did the policy for Oversight of Dual-Use Research of Concern and Pathogens with Enhanced Pandemic Potential put GoF research under?
Which professor attended Harvard for their doctoral degree?
Who is Dr. Geck?
This amino acid substitution in the PB2 gene enhances influenza virus replication in the cooler upper respiratory tract of mammals.
What is E627K?
Two non-CRISPR-based techniques used to give organisms new functions
Transduction and Electroporation
What is the name of the framework that was introduced under the Trump Administration in 2017?
What is HHS P3CO?
Which professor wrote their thesis on the cytoskeleton?
Who is Dr. Anders?