structures/anatomy
upper GI
lower GI
control
control
dysfunction
dysfunction
pharmacology
100

what structures are considered to be part of the upper GI tract?

lower?

mouth, esophagus and stomach

lower: intestines, liver, gall bladder and pancreas

100

salivary amylase is found in the ____ and is responsible for breaking down _____

saliva; carbohydrates

100

true or false: the pancreas in covered in a fibrous capsule, while the liver is not

false; the pancreas is NOT covered in a fibrous capsule, while the liver IS

100

circulation of fat and cholestoral is determined by what organ?

liver

100

what causes activation of the parasympathetic NS to act on the GI tract?

distension of the stomach and a small increase in pH
100

which one causes more dehydration, vomiting or diarrhea?

diarrhea

100

failure to thrive

malnutrition

100

antacids are taken for...

what are two examples

intermittent or mild heartburn

tums (calcium carbonate) and Gaviscon 

200

the upper GI is responsible for...

the lower GI is responsible for...

upper...preparing food to become nutrients

lower...distributes nutrients and there are many enzymes involved

200

which congenital abnormalities fall under the category of an upper GI pathology? why?

cleft palate/cleft lip can lead to feeding and speech impairments
200

which section of the small intestine is the major site of nutrient absorption? what structure increases the general SA for absorption?

ileum; plicae circulares

200

cholecystokinin's primary effect is to

decrease emptying and increase bile production to break down fat

200

what does the release of bicarbonate into the intestines do?

bicarbonate will be released into the small intestine to bring the pH back up 

200

what can PTs do for patients with constipation?

exercise may relieve constipation, buts difficult because patients may not want to exercise due to discomfort/pain and inability to relax the pelvic floor

200

if an individual is having GI problems, they should not be given _____ _______.

if individuals are experiencing pancreatic pain, they cannot be given _____

oral medicine, because it doesn't get absorbed if GI not working well

opioids

200

which proton pump inhibitor is commonly seen on a medication list and is sold OTC

Prilosec

300

list the layers of the gut tube from inner to outer


mucosal

sub-mucosal

smooth circular muscle

longitudinal muscle

serosa

300

what cells are located in the stomach and responsible for producing the enzyme pepsin?

why is this important?

gastric chief cells

they produce pepsin and bicarbonate, which functions to constantly neutralize acidity already located within the stomach

300

which 2 substances are made by the pancreas?

insulin and digestive enzymes

300

as a result of food, protein, caffeine and an increase in pH, the hormone ______will be released from the _____ ____ to increase gastric motility and emptying

gastrin; gastric chief cells

300

sign and symptom of Crohn's disease is

fever, malaise weight loss and RLQ pain

300

if a patient has diarrhea, a PT should be aware because they will have ___ electrolytes and ____ CO.

severe diarrhea can lead to dangerously low levels of _____, which can progress the patient into a state of _______ _______

low; low

bicarbonate; metabolic acidosis 

300

why should PTs care about patients experiencing malnutrition?

healing potential is decreased

energy availability is decreased= decrease endurance

increased risk of osteoporosis

300

what are the two types of acid-reduction medications?

histamine-2 blockers

-pepcid and zantac

proton pump inhibitors

-prilosec and prevacid

400

what does it mean that the mucosal inner is ablative? why is this a good thing?

this layer is designed to wear away, but also provides protection against the sharp things found in the gut tube

400

describe these upper GI infections

candida albicans

HSV type 1

HSV 2

herpes zoster

candida albicans--> opportunistic fungal infection; seen in babies, chemo patients 

HSV type 1--> from kissing, close contact; remains dormant and expresses with stress

HSV 2--> genitals

herpes zoster--> chicken pox

400

list the functions of the liver

maintains BG 

amino acid storage and management

produces clotting factors, lipoproteins and cholesterol

detoxifies drugs and alcohol

blood reservoir

produces bile to emulsify fats

400

which hormone is released from the intestinal mucosa when protein and fat enter the duodenum? 

cholecystokinin

400

which nerves are stimulated with parasympathetic control? what do they do?

CN X (vagus nerve)--> increases motility and digestive secretions like bile to work on the gut

CN VII and CN IX --> saliva and moisture of oral mucosa (works on saliva)

400

what does "coffee-ground emesis" indicate in a patient?

what about "frank red blood?"

they have partially digested blood and they are bleeding somewhere in the mouth or esophagus

red blood is in the vomit

400

for patients with nausea, we should...

take more breaks and avoid certain positions or activities 

400

what are

cholelithiasis

cholecystitis

cholangitis

choledocholithiasis

cholelithiasis--> formation of gall stones

cholecystitis--> inflammation of gall bladder and cystic duct

cholangitis--> inflammation of bile duct

choledocholithiasis--> gallstones obstructing biliary tract

500

give brief detail regarding the 

mesentery

greater omentum

2. double layer of peritoneum that supports intestines and help move blood

3. fatty apron over intestines

500

where can an infection go to from the mouth? how?

the heart via sublingual veins

500

describe how the pancreas helps neutralize acidity of chyme before it enters the intestine

acid and food mixture coming from the stomach is known as chyme. the pH is close to 1, so the pyloric sphincter that connects pancreas to SI opens and allows for bicarbonate to be dumped and help raise the pH

500

secretin from the intestinal mucosa is released when there is a(n) _____ in pH in the duodenum 

decrease

500

central vasoconstriction is done through activation of the ______ NS. what does this do?

sympathetic NS

blood will be taken away from visceral organs in order to supply the brain and limbs. High enough stimulation will empty out whatever is left in the body to make it more functional.

500

what is the main reason that PT's should be aware if the patient has bulimia?

Bulimia causes low energy and may result in possible arrhythmias to electrolyte imbalances

the individual is probably not getting enough energy/nutrients, even though they may look normal, and we don't want to over-prescribe exercise

500

GERD is the result of a defective ...

lower esophageal sphincter pressure or function 

500

hyperbilirubinemia, also known as ______, is considered a _____, not a _____. 

what types are most commonly seen

jaundice

color; disease 

pre-hepatic in newborns

intrahepatic in liver disease

600

what is the peritoneal cavity?

potential space with a small amount of fluid

600

when working with patients that have dysphagia, what do PTs need to consider?

is it easier for them to swallow thin or thick liquids?

they have difficulty swallowing= difficulty with exercise tolerance 

thicker liquids are easier to control 

600

describe how stool is formed and where it is formed. what is feces made of?

most water and electrolytes are absorbed at the end of the GI track and there is not more digestion/absorption of nutrients in the colon (large intestine)

feces contains fiber, old mucosal cells and bacteria

600

gastrin and cholecystokinin differ in that gastrin ______ gastric emptying, while cholecystokinin _____ gastric emptying

increases; decreases

600

Sign and symptom of ulcerative colitis is

Diarrhea, rectal bleeding and abdominal cramping

600

fluid and electrolyte imbalance can impact physical therapy because...

muscle activation could be dysfunctional, they may have an irregular heart rate, feel fatigue, at risk for seizures

600

the lower esophageal sphincter causes GERD when...

this is more common to happen in which position?

it spontaneously relaxes

commonly occurs in supine

600

compare hepatitis of the liver and cirrhosis

what does idiopathic hepatitis mean?

liver "failure" occurs when __-___% of tissue is destroyed

hepatitis: inflammation of liver commonly due to a viral infection

idiopathic= non-alcoholic steatohepatitis (NASH)

cirrhosis: progressive destruction of liver tissue

80-90%

700

what structures allow for large volumes of "stuff" and allows distension when there is a lot of gas build up

the peritoneal cavity and abdominal musculature 

700

swallowing is a _____

reflex

700

how does the liver maintain blood glucose?

when there is an increase in BG, the liver stimulates the process of glycogenesis to form glycogen

when there is a decrease in BG, the liver stimulates the process of gluceoneogenesis

700

what 3 hormones are involved in the control of pH level

gastrin, secretin and cholecystokinin

700

there is too much random info

sorry

700

the most common sites for ulcers are ...

duodenal

gastric 

H. pylori

700

compare the s/s of people are take vast amount of NSAIDS, have high amounts of stress and those with H pylori

             NSAIDS           H pylori            stress

pain       chronic            chronic             acute 

site         gastric            duodenal          gastric

sx           asymp.           epigastric         asymp.

depth     deep                superficial      most superficial 

bleeding  more severe   less         more

700

pancreatitis can have sudden and acute attacks after....

large meals or large amounts of alcohol

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