DNA
Replication
Transcription
Genetic Code
Translation
100
DAILY DOUBLE
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100
To which end of a DNA strand are new nucleotides added?
3'
100
What is the sequence of the RNA produced from the following DNA molecule?
Sense strand: ATGCCCGAC
AUGCCCGAC
100
A mutation results in alanine being substituted for threonine. Based on the properties of the amino acids, is the mutant protein likely to work?
____ (Y/N), because alanine is ______ and threonine is ______.
No, because alanine is nonpolar and threonine is polar.
100
What peptide is produced by the mRNA sequence below?
AAUUUUCCC
Asn - Phe - Pro
200
In a nucleic acid strand, nucleotides are held together by ______ bonds between ______ and _______
covalent; phosphates; sugars
200
What is the name of the newly synthesized top strand?
Leading strand
200
RNA polymerase reads a _______ strand in the _______ direction and synthesizes an RNA in the _______ direction
RNA polymerase reads a template/antisense strand in the 3' to 5' direction and synthesizes an RNA in the 5' to 3' direction
200
There are ____ codons and _____ amino acids.
64; 20
200
The RNA sequence that complements this DNA: T-T-A-G-C-G-A-T-C-T
What is A-A-U-C-G-C-U-A-G-A?
300
Which part of a nucleotide is present at the 5' end of a nucleic acid strand?
Phosphate group
300
Cells are grown in 14N then transferred to 15N for one generation.
What type of strands will the new molecules contain if replication is conservative?
One will have two heavy and one will have two light
300
What 3 things happen to eukaryotic RNAs during RNA processing?
Cap is added; tail is added; RNA is spliced
300
What are the three stop codons?
UGA, UAA, UAG
300
Is the following mutation a frameshift? Explain
WT coding: TTACCCAAT
Mutant coding: TTACCCGGTAAT
No, because 3 nucleotides were inserted. A frameshift results from the insertion of 1, 2, or a multiple of 2.
400
In a DNA molecule, adenine pairs with _____ and guanine pairs with ______.
thymine; cytosine
400
What is the name of the molecule that separates the two DNA strands?
Helicase
400
What is the name of the enzyme that synthesizes an RNA molecule from a DNA sequence?
RNA polymerase
400
Which amino acids are only encoded by one codon? Identify the codon for each one
Meth - UAG and Trp - UGG
400
What codon(s) can pair with an anticodon that has C in the first position, G in the second position, and U in the third position?
ACG
500
Which two DNA nucleotides are purines?
Guanine and adenine
500
What are the red parts of the Okazaki fragments in the box?
Primers
500
Name three differences between DNA and RNA
DNA is double strand while RNA is single; DNA contains T while RNA contains U; DNA contains deoxyribose while RNA contains ribose
500
What anticodon can pair with both codons below? Write the anticodon from 5' to 3'.
5' - ACU - 3'
5' - ACC - 3'
5' - GGU - 3'
500
What type of mutation is shown? If it is a subsitution, what type of substitution is it?
WT antisense: TTCCAAGGG
Mut antisense: TTCCAAGGC
Substitution, missense. CCC (Pro) to CCG (Pro)