Nucleic acid and the nature of the genetic code
Significance of proteins
Protein synthesis
Metabolic pathways
Effect of environment on genotype
100

Groups of three bases on DNA.

What is a triplet?

100

A section of DNA.

What is a gene?

100

The organelle where protein synthesis takes place.

What is a ribsome?

100

Linked biochemical reactions catalysed by enzymes.

What is a metabolic pathway?

100

The physical expression of a genotype. 

What is phenotype?
200

A monomer composed of sugar (deoxyribose or ribose), phosphate and a nitrogen base.

What is a nucleotide?

200

Products of gene expression.

What are proteins?

200

The DNA strand used to make mRNA.

What is the template strand?

200

A substance that fits into the active site of an enzyme.

What is a substrate?

200

Remains unaffected despite phenotype changes.

What is genotype?

300

Ribose

What is the sugar on RNA?

300

Many amino acid molecules joined together in one chain.

What is a polypeptide?

300

The DNA strand that contains the base sequence that will be used in protein synthesis.

What is the coding strand?
300

An interruption in the reaction series preventing the metabolic pathway from progressing to the end. 

What is a metabolic disoder?

300
A mutation where the amino acid sequence stays the same, despite the bases changing in the DNA sequence. 

What is silent mutation?

400

When several codons code for one amino acid.

What is redundancy?

400

Globular proteins that catalyse specific reactions.

What is an enzyme?

400
Contains an anticodon that specifies which amino acid it can carry to the ribosome. 

What is tRNA?

400

A substrate made in the middle of a metabolic pathway needed to make the final product (protein). 

What is an intermediate substrate?

400

Chemical or physical agent that can cause a permanent change in the DNA sequence.

What is a mutagen?

500

A number of 3 base combinations specify one amino acid and these codons often differ by only a single base. E.g. Proline is encoded by four different codons. 

What is degeneracy?

500

The chemical bonds holding a protein together become broken and the protein can longer hold its 3D shape.

What is denature (or denaturation)?

500

Last step of protein synthesis where the mRNA is used to build the a polypeptide chain in the ribosome. 

What is translation?

500
Displacement of bases by one position. 

What is a reading frame shift?

500
Non-genetic influences on phenotype. 

What is environmental factor?

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