Gene Therapy Basics
This fundamental unit of heredity is the focus of gene therapy
What is a gene.
Gene therapy is used to treat this blood disorder caused by a mutation in the HBB gene, leading to misshapen red blood cells.
What is sickle cell anemia.
What sports do we do? (1 each)
This U.S. agency oversees the approval of gene therapies to ensure they are safe and effective.
What is the FDA.
Gene therapy is designed to fix or replace these parts of your DNA that carry genetic instructions.
What are genes
Gene therapy works by modifying this molecule, which carries genetic instructions.
What is DNA.
Luxturna, a gene therapy, was approved to treat a rare form of this sensory impairment caused by mutations in the RPE65 gene
What is blindness.
What is Mrs. Rylands favorite book?
What is Pride and Prejudice.
Ethical debates in gene therapy often center on this type of genetic modification, which affects sperm, eggs, or embryos.
What is germline editing.
This continent approved the first commercial gene therapy treatment, Glybera, in 2012.
What is Europe.
In gene therapy, vectors such as viruses are used to deliver genetic material to these types of cells.
What are target cells.
Gene therapy aims to restore the missing clotting factor in people with this inherited bleeding disorder.
What is hemophilia.
Who is the current AP bio teacher.
What is Mrs. Autrey.
One major ethical concern in gene therapy is ensuring fair access, especially for patients from this type of socioeconomic background.
What are low-income or undeserved backgrounds.
The first successful human gene therapy trial happened in this decade.
What is the 1990’s.
This type of gene therapy involves adding a functional copy of a gene to replace a faulty one.
What is gene replacement therapy.
Patients with mutations in the CFTR gene benefit from gene therapy research for this condition affecting the lungs and digestive system.
What is cystic fibrosis.
What school’s does battlefield basketball play this week.
What ism Osborn, Forest Park, Patriot.
The 1999 death of Jesse Gelsinger during a clinical trial raised ethical questions about the risks of this experimental treatment.
What is gene therapy.
This viral delivery tool is commonly used in gene therapy to insert healthy genes into cells.
What are viruses.
This term describes gene therapy that is passed down to offspring because it modifies reproductive cells.
What is Germline gene therapy.
The first FDA-approved gene therapy, Kymriah, treats this type of cancer that affects the blood and bone marrow.
Leukemia.
Name all P.E. Teachers.
What is Mr. Bills, Mr. Burkhart, Mrs. Link, Mrs. Ward.
The use of gene editing tools like CRISPR in humans is regulated internationally under this type of agreement to prevent misuse.
What are bioethical guidelines.
The first FDA-approved gene therapy, Luxturna, restores vision by targeting this part of the body.
What are the eyes.