Inheritance Games
Cancer
(It's Back Again)
100

This is what we call someone who shows no disease symptoms, despite having a copy of a mutant allele.

What is a carrier?

100

This cancer treatment seeks to induce p53 to activate, but can damage healthy tissue.

What is radiation?

200

This inheritance pattern requires two mutated genes to cause disease expression.

What is autosomal recessive?

200

This is the primary cell type affected by leukemia. 

What are neutrophils?

300

Straight-haired Mike and curly-haired Molly have three wavy-haired children, showing this inheritance pattern.

What is incomplete dominance?
300

This step comes after dysplasia and before invasive cancer, and is a tumor in a specific tissue.

What is in situ cancer?

400

This dominance pattern is exhibited in the ABO blood groups. 

What is codominance?

400

Mutations in BRCA2 are common in Scandinavia due to this phenomenon, in which a small group of individuals colonize a new area.

What is the founder effect?

500

This term is used when the expression of one gene pair masks or modifies the expression of another. 

What is epistasis?

500

Philadelphia chromosome, a translocation between chromosomes 9 and 22, results in this protein being produced. 

What is BRC-ABL1?

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