History of Genome Sequencing
The Science
Behind It
Humans and
Animals
Medicine and Disease
100

This is the collection of all of the DNA in an organism, which includes nuclear, mitochondrial, and, in some cases, chloroplast DNA.

What is a genome?

100

This form of substitution leads to a change in the amino acid and, therefore, protein structure, which can cause changes in the phenotype.

What is a non-synonymous substitution?

200

1. Computers are slow and can have difficulty storing so much data

2. It can be costly and confusing to determine who owns and pays for the data

3. Biological repeats in DNA create complications

are all examples of this.  

What are the problems with sequencing a genome? 

200

These are the four steps to sequencing a genome.

What are Sequence, Assemble, Annotate, and Analyze?

200

This diagram reflects shared homology, or shared ancestry, between species.

What is an evolutionary tree?

300

This field of research is where the genomic features of different organisms are compared to provide insight into species evolution and organismal physiology.

What is comparative genomics?

300

This disease causes a buildup of glutamine amino acids in the poly-Q tracts of the Htt gene.

What is Huntington's Disease?

500

This category of cancers makes up roughly 90% of all cancers and arises from a mutation in epithelial cells.

What are carcinomas?

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