What you lookin' at Willis?
A property of antihistamines, TCAs, Antispasmodics, Skeletal Muscle Relaxants, and Alpha-2-agonists that causes confusion, dry mouth, and constipation
What is Anticholinergic effects?
NSAIDs increase the risk of _____ in older adults due to decreased GI Motility
What is bleeding?
Go to sleep aid for most older adults that SHOULD NOT be their go-to drug
What is Benadryl (diphenhydramine)?
Popular OTC antihistamine used for its side effect as a sedative (but shouldn't be!)
What is Benadryl (diphenhydramine)?
Benzodiazepines with this DOA increase risk of cognitive impairment, delirium, falls, fractures, & MVAs in older adults
What are all Benzodiazepines?
Blood Pressure related side effect of Alpha-1-blockers, Alpha-2-agonists, and TCAs
What is orthostatic hypotension?
PPIs (reduce/eliminate) the risk of GI Bleeds in older adults who take NSAIDs
What is reduction?
Alpha-2-agonist with high risk of adverse CNS effects, bradycardia, and orthostatic hypotension that should not be used as a first-line antihypertensive
What is clonidine?
OTC drug that should be used with caution in adults ≥80 years old due to lack of evidence of benefit v. risk for primary prevention of cardiac events
What is aspirin?
Commonly used long-acting sulfonylurea with greater risk of prolonged hypoglycemia in older adults
What is glyburide?
Older adults have an increased risk of _____ when they take drugs that cause ataxia, impaired psychomotor function, and /or syncope
What is falls?
NSAID with the most adverse effects of all
What is indomethacin?
Class of antihypertensives whose main side effect is orthostatic hypotension (especially 1st dose hypotension) that should be avoided in older adults
What are Alpha-1-blockers?
"OTC Drug" that should be avoided, especially in afternoon & evening hours by older adults with insomnia
What is caffeine?
Group of drugs that has adverse effects similar to BZDs in older adults & which only provide minimal improvement in sleep latency and duration
What are non-benzodiazepine hypnotics?
This risk is increased in older adults with heart failure who take spironolactone, especially >25 mg/day or with concomitant NSAID, ACE-I, ARB, or K+ supplements
What is hyperkalemia?
NSAIDs have the potential to promote _____ _____ so should be avoided in patients with heart failure
What is fluid retention?
Group of drugs that should be avoided as first-line treatment for AFib in older adults (& instead focus on rate control)
What are anti-arrhythmics?
OTC Laxative that should be avoided due to potential for aspiration when used orally
What is mineral oil?
Group of drugs poorly tolerated by older adults due to anticholinergic effects, sedation, risk of fracture, & whose effectiveness @ doses tolerated by older adults is questionable
What are skeletal muscle relaxants?
Drug with increased risk of toxicity due to slow renal clearance that should be avoided at doses > 0.125 mg/day in older adults with heart failure
What is Digoxin?
What is 80 years old?
Class of drugs that should be avoided as first-line treatment of depression due to high anticholinergic properties & potential to cause sedation & orthostatic hypotension in older adults
What are TCAs
What is Claritin (loratidine)?
The most constipating Calcium Channel Blocker
What is Verapamil?