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The mechanism of action of drugs like PantoPRAZOLE, esomePRAZOLE, and LansoPRAZOLE is
Proton Pump Inhibitors:
1. Decrease gastric acid secretion
**PPI's are the most potent inhibitors of gastric acid secretion**
**Last longer than other therapies and has faster effects***
Indications for the use of Proton Pump Inhibitors includes which of the following?
(6 options)
GERD
PUD
Ulcers (Gastric/Duodenal)
Zollinger-Ellison
H. pylori
Heartburn
This adjuvant antidiarrheal agent may cause temporary darkening of the tongue or stool.
Bismuth subsalicylate (Pept-Bismol)
This prototype drug of the bulk forming laxatives acts as soluble fiber that becomes gel-like when mixed with water
psyllium (Metamucil)
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Dr. Moehl
A patient has been taking PantoPRAZOLE for 4 weeks. What symptom would show that this medication has been EFFECTIVE.
A decrease in Heartburn symptoms
It is a CNS depressant and antipsychotic drug used in the treatment of nausea and vomiting
promethazine (Phenergan)
This antidiarrheal is a Scheduled V controlled substance
diphenoxylate with atropine (Lomotil)
This cathartic is ideal for bowel cleansing prior to a colonoscopy or procedure.
polyethylene glycol - electrolyte solution (PEG-ES, NuLYTELY, GoLYTELY)
Sushi is this professor's favorite thing to eat
Prof. Villanueva
Taking this drug class commonly used for the management of GERD can result in kidney disease, fractures, infections, and vitamin deficiencies when used long term.
Give one example of a drug in that class.
What are Proton Pump Inhibitors
Pantoprazole (Protonix)
Esomeprazole (Nexium)
Lansoprazole (Prevacid)
Dexlansoprazole (Dexilant)
Omeprazole (Prilosec)
This drug is useful for patients with ulcers and works by coating ulcers and improve their healing
Sucralfate
For prevention and treatment of ulcers. Lasts 4-8 weeks. No actual effect on acid besides being a barrier.
**Can delay absorption of other drugs. Take other medication 2 hours before sucralfate**
This synthetic derivative of meperidine can be found over the counter to relieve diarrhea.
loperamide (Imodium)
This group of cathartic puts clients with heart failure at risk for fluid retention and edema
saline cathartics containing sodium
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Dr. Ayala
What is a common adverse effect associated with the use of an ALUMINUM containing antacid?
Constipation
Aluminum-containing antacids are constipating, so the client would be instructed to take a stool softener or additional bulk-type laxatives to relieve this uncomfortable side effect.
It is the first drug of choice for post op N/V or chemo-induced N/V
ondansetron (Zofran)
Clients that have an aspirin allergy should avoid this over the counter antidiarrheal
Bismuth subsalicylate (Pepto-Bismol)
When taken by mouth, this lubricant laxative can cause lipid pneumonia in clients that have difficulty swallowing.
mineral oil
44% of this professor's diet is nitro cold brews. The remaining 76% consists of nitro cold brews.
Prof. Wyatt
A client has been given lansoprazole for the chronic management of Zollinger-Ellison syndrome. The nurse instructs the client to take which product for PAIN while taking this medication?
Pain as in normal pain - body aches, headaches, injury related pain NOT stomach pain
Zollinger-Ellison syndrome is a hypersecretory condition of the stomach, associated with increased risk of problems from irritation of the stomach lining. The client would take acetaminophen for pain relief. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen sodium, would be avoided, as would aspirin, because they are potential stomach irritants.
The nurse is reviewing the prescriptions for a newly admitted client. The nurse sees a prescription for intravenous pantoprazole but does not see any gastrointestinal conditions in the medical record. How would the nurse interpret this prescription?
It is used as a PROPHYLACTIC measure
Pantoprazole is a proton pump inhibitor and is commonly used as a gastrointestinal prophylactic measure to prevent stress ulcers.
This antidiarrheal has a black box warning for torsades de pointes, cardiac arrest and death
loperamide (Imodium)
This stimulant cathartic prototype drug should not be taken more than 1 week because it can cause serum electrolyte and acid-base imbalances
bisacodyl (Dulcolax)
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Pharmacology at the TWU Houston campus!