Lupus nephritis
Membranous nephropathy
Focal segmental glomerulosclerosis
Organized Deposits
Monoclonal
100
This class of lupus nephritis is characterized by mesangial immune deposits only
What is class I or II?
100
This antigen is most commonly associated with primary membranous nephropathy
What is anti-PLA2R?
100
This describes pattern of injury seen in FSGS on biopsy
What is focal and segmental sclerosis?
100
This disease shows Congo red-positive deposits
What is amyloidosis?
100
This disease shows linear IgG deposition along GBM and TBM
What is MIDD?
200
This lupus class is most associated with "wire loop" lesions on light microscopy
What is class IV?
200
This immunofluorescence pattern is seen in membranous nephropathy
What is granular IgG along GBM?
200
This EM finding helps distinguish primary and secondary FSGS
What is diffuse foot process effacement?
200
These fibrils measure approximately this size in amyloidosis
What is 8-12 nm?
200
This subtype involves light chains only
What is light chain deposition disease?
300
This complement pathway is primarily activated in lupus nephritis
What is the classical pathway?
300
These deposits are located in this part of glomerulus
What are subepithelial deposits?
300
This variant of FSGS is associated with collapsing glomerulopathy
What is APOL-associated FSGS?
300
This disease has larger fibrils and is Congo red negative
What is fibrillary glomerulonephritis?
300
This biopsy technique is required to demonstrate monoclonality definitively
What is immunofluorescence? Kappa and lambda restriction
400
This serologic marker correlates best with lupus nephritis activity
What is anti-dsDNA? Low complement levels also acceptable answer
400
This complement complex mediates podocyte injury in membranous nephropathy
What is C5b-9?
400
This trial showed MMF+ dexamethasone was not superior to cyclosporine
What is FSGS clinical trial?
400
This condition is associated with microtubular structures and often lymphoproliferative disease
What is immunotactoid glomerulopathy?
400
This condition is associated with plasma cell dyscrasia but does not meet criteria for multiple myeloma
What is MGRS?
500
This class of lupus nephritis may present with nephrotic syndrome and resembles membranous nephropathy
What is class V?
500
This trial showed rituximab was non-inferior to cyclosporine and superior for maintaining remission?
What is MENTOR trial?
500
This pathologic feature represents adhesion between glomerular tuft and Bowman's capsule
What are synechiae?
500
This protein is sensitive marker for fibrillary GN
What is DNAJB9?
500
This distinguishing feature separates MIDD from amyloidosis on EM
What is non-organized deposits vs fibrillary in amyloid?