What are/How do GLP-1s work?
What does GLP-1 stand for?
Glucagon-like peptide-1
What is the brain's appetite control center?
The Hypothalamus
The gut doesn't only absorb food. What else can it do? (at least 1)
Regulating hunger, absorbing nutrients, eliminating waste
What are some of the most common side effects? (list at least 3)
Nausea, vomiting, diarrhea, constipation, bloating
What were GLP-1s originally created for?
These drugs were actually first created to treat Type 2 diabetes but doctors then noticed patients were also losing significant weight
What happens to cravings?
They are reduced or erased
GLP-1s make the food stay in your stomach longer and stretches it. It then activates ____ receptors that tell the brain you are full
Stretch
What happens when a patient ends up eating too little?
Fatigue and nutrition deficiencies
GLP-1 drugs increase the release of what hormone?
How does the brain's reward system work?
Manipulating dopamine
What is the communication system between digestive tract and nervous system called?
The gut-brain axis
What is one of the two rare risks?
Pancreatitis and thyroid risks
Rather than acting on only one organ GLP-1 drugs affect...(get at least 3/4)
The brain, pancreas, stomach, and intestines
GLP-1 receptors found in parts of brain that control...(list at least 2/3)
Hunger, fullness, and reward
They slow digestion by delaying what process?
Stomach emptying
What can happen when fat is broken down too quickly?
Gallstones
What process slows down how fast food leaves the stomach?
Gastric emptying
Reduce activity in neurons that stimulate ____, increase activity in ones that stimulate ____
Hunger, fullness
Because food moves slowly through your intestines, what human process does it affect
Bowel movements
What parts of the body does the change in hormone signals effect?
Trick question! It affects the whole body