Hormones
This hormone, secreted by pancreatic beta cells, suppresses gluconeogenic enzymes
Insulin
This allosteric regulator, based on energy charge, suppresses both Pyruvate Carboxylase and PEP carboxykinase
ADP
Insulin would lead to the buildup of fructose-2,6-BP, which would inhibit this enzyme
Fructose-1,6-bisphosphatase
The inhibition of this complex decreases ATP concentration
Complex I
This covalent modification by P300 and Bat3 leads to the degradation of PEP carboxykinase
Acetylation
This hormone is linked to the CREB protein
Glucagon
This allosteric regulator, based on energy charge, inhibits Fructose-1,6-bisphosphatase
AMP
The dual function enzyme is phosphorylated by Protein Kinase A at this amino acid (Don't need number)
Serine
Metformin inhibits this enzyme, that lowers the production of DHAP
mGPD
This molecule helps stabilize the bond between citrate and Fructose-1,6-bisphosphatase
water
This hormone forms the GR complex that enters the nucleus
Glucocorticoid
This allosteric regulator, which operates between Fructose-1,6-bisphosphatase and Phosphofructokinase, is hormonally controlled
Fructose-2,6-bisphosphate
This hormone leads to the dephosphorylation of Fructose-2,6-BP
Glucagon
Diabetes causes an increased concentration of this molecule that increases the concentration of DHAP
This will happen to the weight of a person if they suffer from hyperthyroidism
Decrease
This drug is used to treat thyroid hormone deficiency
Levothyroxine
This allosteric regulator is a Krebs cycle intermediate that activates Fructose-1,6-bisphosphatase
Citrate
This enzyme dephosphorylates the dual enzyme in the presence of insulin
Protein phosphatase 1
If one exercised while on Metformin, there would be a buildup of this product
Lactate
This molecule, created by adenylate cyclase from glucagon activation, leads to the phosphorylation of CREB
cAMP
This protein, activated by insulin, goes on to suppress FOX1 and CRTC2 transcription factors
Protein Kinase B (AKT)
This allosteric activator can be increased through the breakdown of fatty acids
Acetyl CoA
The name of this half of the dual function enzyme phosphorylates fructose-6-P to form fructose-2,6-BP
phosphofructokinase-2
This protein inhibits the INSR through phosphorylation
protein kinase Cε
This transcriptional regulator activated by CREB helps FOX01 in the transcription of PEPCK and glucose-6-phosphatase
PGC-1α