Covering the Basics
Experimental Design!
Disease in the microbiome
100
This term describes the entire habitat including microorganisms, their genomes, and environmental conditions

Microbiome

100

Which sequencing method identifies which bacteria are present by targeting a conserved ribosomal gene?

16S rRNA gene sequencing

100

C. difficile infection is primarily mediated by what type of molecules that induce host damage, cell death, and immune dysfunction.

Bacterial Toxins

200

This term refers to the assemblage of microorganisms in a defined environment?

Microbiota

200

Which part of the GI tract contains the highest of microbes?

The colon

200

What is a traditional environmental risk factor for C. difficile infection?

Hospitalization

300

What is the collection of genomes and genes from all members of a microbiota called?

Metagenome

300

What diagram depicts the evolutionary relationship + history among a group of organisms

Phylogenetic Tree

300

What procedure first performed at UMMC, uses exchange of the stool to treat recurrent CDI?

FMT (Fecal Microbiota Transplant)

400

What term describes a disturbance in a biological system, such as altered bacterial composition?

Dysbiosis

400
Approximately what percentage of gut microbes have never been cultured? (will accept anything within 10% accuracy!)

90%

400

Which antibiotic is used to treat fulminant CDI?

Vancomycin

500

More than 90% of gut microbes belong to which two phyla? (Name either or :))

Firmicutes & Bacteroidetes

500

In what decade was the Human Microbiome Project Launched?

2000s

500

Which namesake rule describes the chance of recurrence for CDI?

20 -> 40 -> 60%

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