Background
(History + MOA)
(History + MOA)
Catechins, the active chemical in Green Tea, are thought to have the most cardiovascular benefit due to their ______ effects.
What are antioxidant effects?
This form of green tea consumption is more likely to cause GI irritation and hepatotoxicity (Brewed tea OR capsule/extract)
What is capsule/extract?
The clinical trial studied in this presentation was what type of trial?
What is a Randomized Controlled Trial?
This was a federal law enacted in 1994 that regulates the manufacturing, marketing, and labeling of dietary supplements.
What is DSHEA?
These are the two countries where Green Tea became the most popular, and they still are today!
What are China and Japan?
Name a common side effect of green tea consumption mentioned in this presentation (there were 3)
Gastrointestinal issues
Caffeine sensitivity
Iron absorption
The clinical trial in this presenation studied the effects of catechins and this additional chemical on cholesterol levels.
What are theaflavins?
Dr. Kelly Shields holds this title in the Raabe College of Pharmacy.
After green tea's discovery in 2737 BC, people began to use it as an herbal medicine, as they believed it was effective for ________ (name 1 of the 3 benefits)
What are Lowering body temperature, Aiding digestion, or Alertness?
Name one major drug interaction with Green Tea, AND the effect that is produced when taken concomitantly (3 were mentioned in this presentation)
Atorvastatin (Lipitor): 300-600 mg - ↓ plasma levels ~24%
Ephedrine + caffeine: ↑ BP + ↑ risk of MI, stroke, seizures, death (also risk of CAD, Cardiomyopathy, or chronic hypertension in long-term users.)
Warfarin (Coumadin): Vitamin K content ↓ anticoagulant effect + ↑ clot risk
Lisinopril: ↓ antihypertensive effect due to caffeine’s ability to narrow blood vessels.
Diuretics: ↑ hypokalemia risk (Especially with loop and thiazide)
Stimulants (pseudoephedrine, caffeine): Increase heart rate and blood pressure
In the presented study, these 2 objective measures (ex. TG, TC, LDL, or HDL) were shown to have a statistically significant benefit after taking the treatment capsule for 12 weeks
What are TC + TG?
This is the room number of the room we are in right now (ex. HP ???)
What is HP 157?