Topic 1
The process of metabolic biosynthetic that uses energy to build ordered structures from smaller building blocks.
What is anabolism?
The final product of DNA.
What are proteins?
One of the three interfaces of protein binding.
What is Surface-String protein binding?
Break down nucleic acids by hydrolyzing bonds between nucleotides.
What is the function of nucleases?
The complete store of information in an organism’s DNA.
What is a genome?
Mechanism by which DNA is replicated where a new nucleotide is joined to a growing DNA chain based on if it can pair with the appropriate nucleotide on the parental DNA strand.
What is templated polymerization?
Peptide bonds that allow for rotation around the alpha carbon in a polypeptide.
What are Phi/Psi bonds?
An analysis method that looks for conserved amino acid sequences between protein family members in order to identify the sites within a protein domain that are critical to its function.
What is evolutionary tracing?
A process that removes a water molecule to create bonds and join peptides together.
What is dehydration synthesis?
The nucleotide base that replaces thymine in RNA.
What is uracil?
Composed of a base, a pentose sugar and one or more phosphate groups.
What are Nucleotides?
Made up of carbon, oxygen, hydrogen, nitrogen, and an R' group; they are grouped into four families: acidic, basic, uncharged polar, or nonpolar.
What are Amino Acids?
The first step in Enzyme Catalysis.
What is Substrate Binding?
Awarded the 1962 Nobel Prize in Medicine or Physiology for the discovery of the DNA structure.
Who are Watson and Crick?
An alpha helix breaker.
What is Proline?
Changes in the nucleotide sequence that can arise from the mistakes that occur during DNA replication.
What is Intergenic Mutation?
This helps those structures that cannot self-assemble.
What are Assembly Factors?
Conformational change in a protein where an alpha helix shifts between different structural states.
What is Helix Switch?
Mutations that are introduced into known genes to see what traits are altered through that change.
What is Reverse Genetics?
Physical obstruction and restricted access to specific regions of the amino acid that are caused by bulky side chains.
What is Steric Hindrance?
Genetic information is stored in DNA and flows from DNA to an RNA intermediate and then to protein.
What is the Central Dogma?
Protein structure that is not present in all proteins.
What is the Quaternary Level of Protein Structures?
The binding of allosteric protein to the allosteric site is a good fit and the allosteric modifier is having a positive effect on the substrate binding.
What is Positive Regulation?
Process that utilizes ubiquitin to degrade proteins
What is ubiquitination?
In Michaelis-Menten enzyme kinetics, it is the value at which the enzyme has become 100% saturated by the substrate.
What is the Vmax?