What is robust airway inflammation and accumulation of apoptotic cells?
100
This is the organ most affected by CF.
What are the lungs?
100
This regulator is shown to still be able to induce epithelial cell efferocytosis in vitro.
What is CTFR?
200
These type of cells build up in the airways
What are apoptotic cells?
200
How were actin fibers observed?
Fluorescent staining
200
What is the name of the channel that CFTR controls?
What is Chloride Channel
200
The name of the protein that CFTR deficiency increases?
What is RhoA protein
200
To determine whether CFTR was involved with regulation of
efferocytosis, primary CTFR positive and negative epithelial cells were cocultured with cells of this type.
What are apoptotic Jurkat T cells?
300
The expression of these receptor is altered
What are efferocytosis receptors?
300
This type of cell was isolated for the study.
What are human airway epithelial cells?
300
What were the CFTR-sufficient cells treated with?
What is Channel blocker
300
A lack of this process leads to infection and fluid build up
What is phagocytosis?
300
CTFR deficiency has shown a substantial decrease in efferocytosis as a result of the increase of this type of regulator
What is RhoA?
400
Cystic fibrosis is often associated with the inflammation of epithelial cells as a result of the inappropriate release of proinflammatory inhibitors, such as this.
What is Interleukin 8 (IL-8)?
400
This type of assay was performed on in vitro?
What is phagocytosis assay?
400
This is what CFTR stands for
What is cystic fibrosis transmembrane conductance regulator?
400
This was the purpose of the experiment
What is determining whether CTFR deficiency impairs phagocytosis of apoptotic cells and regulation of inflammatory mediator release?
400
Apoptotic cells were shown to induce IL-8 production by CFTR?-negative epithelial cells in a manner that is independent of this.