Key Concepts
The person or group of persons who must assume responsibility for the well-being of animals used in research, teaching or testing
Who is all of those who care for, use or produce these animals?
A standard or guideline that specifies in detail a method, technology or technique for achieving a desire outcome.
The Attending Veterinarian must/should be provided sufficient authority and access to animals.
What is must?
This role in an animal care and use program bears ultimate responsibility for the Program and has the authority to allocate resources.
What is the Institutional Official?
The recommended width of an animal facility corridor to facilitate movement of personnel/equipment
What is 6-8 feet?
This organization provides voluntary accreditation to animals care and use programs and uses the Guide as a primary standard.
What is AAALAC International?
This describes what a “must” statement in the Guide indicates
What is an action considered an imperative and mandatory duty or a requirement of providing humane care and use to animals?
BONUS: Name the AAALAC site visit finding...
Veterinary consultation must/should occur when pain or distress is beyond the level anticipated in the protocol description or when interventional control is not possible.
What is must?
This role in an animal care and use program is responsible for the assessment and oversight of an Institution’s Program components and facilities.
What is the IACUC?
The recommended dimensions of animal room doors to allow easy passage of racks and equipment.
What is 42" x 84”?
A: This regulatory body requires institutions to use the Guide as a basis for developing and implementing an institutional program for activities involving animals
What is the Public Health Service (PHS)?
A standard or guideline describing a desired outcome while providing flexibility in achieving this outcome.
What is a performance standard?
BONUS: Provide examples of a performance standard
The BMBL (Biosafety in Microbiological and Biomedical Laboratories) reference must/should be consulted for appropriate facility design and safety procedures where biological agents are used.
What is should?
The Institution of an animal care and use program must develop methods for reporting and investigating these types of concerns.
What are animal welfare concerns?
The minimum recommended diameter of drainpipes in an animal facility.
What is 4” (10.2 cm)?
BONUS: Name the larger diameter recommended for areas like dog kennels, Ag animal facilities.
These are the 3Rs as listed in the Guide. Bonus: These are the originators of this concept.
What are Replacement, Refinement and Reduction?
Bonus: Who are Russell and Burch?
This type of statement in the Guide indicates a strong recommendation for achieving a goal with the understanding that individual circumstances might justify an alternative strategy.
What is a should statement?
BONUS: Name the AAALAC site visit finding
Animal protocols proposing food/fluid regulation must/should evaluate 1. necessary level of regulation, 2. potential adverse effects and 3. method for health/well-being assessments.
What is must?
(Guide indicates evaluation of these 3 factors is required)The primary oversight responsibilities in an animal care and use program rest with these three elements, or “legs of a stool”.
What are the Institutional Official, the Attending Veterinarian, and the IACUC?
The recommended range around the set point at which dry bulb-temperatures should be maintained in animal rooms.
What is +/- 1°C (2°F)?
This is the definition of “animal” in the Guide.
What is “any vertebrate animal (ie traditional laboratory animal, agricultural animals, wildlife, aquatic species) produced for or used in research, testing or teaching”
The application of professional judgment but qualified, experienced, individuals to a task or process over time, an approach that has been demonstrated to benefit or enhance animal care and use.
What is a practice standard?
BONUS: Name sources on which practice standards are based.
Veterinary care must/should be provided if lesions or illness associated with restraint are observed.
What is must?
At minimum, the constitution of the IACUC includes this number of members and these roles according to the Guide.
What is 4 - AV, practicing scientist (animal user), non-scientist, public member (non-affiliated, not an animal user)?
The recommended range around the set point at which relative humidity should be maintained in animal rooms.
What is +/- 10%?