Basic Science GBA
The tenth cranial nerve
What is the vagus nerve?
The first drug that was found to treat infections caused by a wide range of bacteria.
What is penicillin?
The procedure/therapy utilized by clinicians to treat GI disorders that has been adopted into labs to understand the role of the gut microbiome on psychiatric disorders.
What is fecal matter transplant?
Foods or supplements that contain live microorganisms intended to maintain or improve the "good" bacteria (normal microflora) in the body.
What are probiotics?
The three types of literature when considering your source.
What are primary sources, secondary sources, and tertiary sources?
The behavioral assay that measures anxiety in rodents in psychiatric disorders (one we talked about several times throughout the semester).
What is the elevated plus maze?
The term that Charles Scott Sherrington gave the neuronal gaps in 1897.
What are synapses?
The treatment that was found to improve John's anxiety symptoms in The Psychobiotic Revolution when Prozac and other SSRIs exacerbated them.
What are targeted antibiotics (minocycline specifically)?
Foods (typically high-fiber foods) that act as food for human microflora.
What are prebiotics?
The appropriate evaluation that is utilized when reading scientific research, deciphering fact from propaganda, and determining whether the author's POV is objective and impartial.
What is objective reasoning?
Single-celled organisms that are not visible to the naked eye.
What are microbes?
The first scientist to observe and record bacteria from plaque scrapings from his teeth through a microscope.
Who is Antonie van Leeuwenhoek
The hypothesis that states PD is initiated from pathogens involved in the gut/GBA.
What is the dual-hit hypothesis?
The profile of the bacterial load in the placenta is similar to that of the mother's __________, which can be altered by a mother's diet.
What is mouth?
The award that was created by Dr. Jonathon Eisen given to the article, "UNC Babies on Cognitive Development."
What is the 'Overselling the Microbiome' award?
The correct order of the hierarchy of biological classification (taxonomy).
What is Kingdom, Phylum, Class, Order, Family, Genus, Species
The philosopher that claimed "All disease begins in the gut."
Who is Hippocrates?
The disorder that is involved in the gut microbiome modulating GBA glycerophospholipid metabolism in a region-specific manner.
What is depression?
The species of bacteria that dominates the vaginal microbiome.
What is Lactobacillus?
A common problem in GBA research where results are deemed as basically causal despite other factors, mixed results, and confounding variables.
What is oversimplification?
The nerve/pathway of the anti-inflammatory reflex loop that modulates circulating levels of proinflammatory cytokines
What are vagus nerve efferents?
The disease that the Boy in the Bubble suffered from.
What is severe combined immunodeficiency (SCID)?
The neurodegenerative disease associated with chronic H. Pylori infections leading to hyperphosphorylation of tau proteins.
What is Alzheimer Disease?
The amino acid involved in the synthesis of kynurenine, indole, melatonin, and serotonin, which aids in the regulation of the sleep-wake cycle.
What is tryptophan?
A common problem in GBA research where one topic and its findings gets expanded to apply to other topics without proper analysis.
What is overinterpretation?